{"id":"W2150515158","doi":"10.1074/jbc.m103921200","title":"Demethylase Activity Is Directed by Histone Acetylation","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":293,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Histone methylation; Histone methyltransferase; Demethylase; Histone; Biology; Chromatin; Histone code; DNA methylation; Acetylation; Histone H2A; Methylation; Epigenomics; Cell biology; Genetics; DNA; Nucleosome; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002962799,0.0001387761,0.0001933452,0.00001579827,0.00005418634,0.00001488964,0.0001596387,0.0003123655,0.0001749784],"category_scores_gemma":[0.0002869667,0.0001083854,0.0001498201,0.00009559689,0.00007220124,0.000005371933,0.00004817811,0.0001781819,0.000003027237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003344386,"about_ca_system_score_gemma":0.00004061624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000325733,"about_ca_topic_score_gemma":4.02394e-7,"domain_scores_codex":[0.999119,0.00005816353,0.0003021807,0.0001961204,0.0001532689,0.0001712565],"domain_scores_gemma":[0.9991587,0.00002854113,0.0003409763,0.0001606393,0.0001811512,0.0001299668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001871475,0.0001196029,0.005652693,0.000005647747,0.00003423845,0.00000527633,0.000007094789,0.000009134396,0.9848361,2.960097e-7,0.002278908,0.006863853],"study_design_scores_gemma":[0.0004150359,0.0002255995,0.004227494,0.00000624149,0.00001424081,0.00002733961,0.000008510697,0.00003022258,0.931622,0.00008535598,0.06320672,0.0001312194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921362,0.003829053,0.002484899,0.0002980418,0.0000757594,0.00004107115,0.00001386836,0.000009080302,0.001112066],"genre_scores_gemma":[0.9957165,0.002484109,0.0005930318,0.00009775568,0.0003505837,0.000001763811,0.00004164517,0.00000943405,0.0007052081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06092781,"threshold_uncertainty_score":0.441983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02030720920699561,"score_gpt":0.2903616947925624,"score_spread":0.2700544855855667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}