{"id":"W2150515158","doi":"10.1074/jbc.m103921200","title":"Demethylase Activity Is Directed by Histone Acetylation","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":293,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Histone methylation; Histone methyltransferase; Demethylase; Histone; Biology; Chromatin; Histone code; DNA methylation; Acetylation; Histone H2A; Methylation; Epigenomics; Cell biology; Genetics; DNA; Nucleosome; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003084433,0.0002428906,0.0003165715,0.0001918053,0.0001940897,0.000578008,0.0003035624,0.0003495169,0.001276154],"category_scores_gemma":[0.0003825648,0.0002089909,0.0004830818,0.0001632065,0.000396027,0.0004196951,0.0003772113,0.000683807,0.0008279229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003406449,"about_ca_system_score_gemma":0.0002400274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004974114,"about_ca_topic_score_gemma":0.0005888579,"domain_scores_codex":[0.999715,0.00003316102,0.00003105259,0.0001233855,0.00006705133,0.00003014221],"domain_scores_gemma":[0.9997379,0.00006090793,0.00006585548,0.00008130167,0.00003455469,0.00001940947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000465514,0.000008993959,0.0004758869,0.00007644566,0.00001719012,0.00003647984,0.00002066531,0.00008927548,0.994524,0.0008874735,0.0000719408,0.003745097],"study_design_scores_gemma":[0.000005961539,0.00006968393,0.003074568,0.00000724967,0.00001314723,0.0001619032,0.00001565661,0.0005423893,0.9891078,0.0002831127,0.006712312,0.000006071982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8629501,0.01672939,0.1024084,0.0008683247,0.0003712346,0.0001035251,0.0009645268,0.0008203816,0.014784],"genre_scores_gemma":[0.9798068,0.003863069,0.01072529,0.0001842499,0.00003703057,0.0000375434,0.0005819041,0.0000457448,0.004718449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001276154,"threshold_uncertainty_score":0.004269183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02030720920699561,"score_gpt":0.2903616947925624,"score_spread":0.2700544855855667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}