{"id":"W2150584498","doi":"10.1139/v03-014","title":"Regioselectivity of Meisenheimer complexation in reaction of oxygen-centred nucleophiles with picryl aryl ethers: Polar vs. SET mechanisms","year":2003,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Regioselectivity; Adduct; Nucleophile; Steric effects; Aryl; Ether; Medicinal chemistry; Structural isomer; Methoxide; Alkyl; Stereochemistry; Organic chemistry; Ion","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004689148,0.0002409102,0.0005453163,0.00009547627,0.00004570989,0.00001517138,0.0002969305,0.0002786553,0.001229881],"category_scores_gemma":[0.0006950762,0.0002450467,0.000131482,0.0003230472,0.0001781895,0.0001188756,0.000008754655,0.0004710241,7.879844e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004328824,"about_ca_system_score_gemma":0.001548846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001272962,"about_ca_topic_score_gemma":0.0006191467,"domain_scores_codex":[0.9983293,0.00005365412,0.0007007152,0.0002374132,0.0003378102,0.0003410903],"domain_scores_gemma":[0.9977291,0.0001498285,0.001013609,0.0004070079,0.0003132136,0.0003872449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001039327,0.00006365623,0.001989572,0.000270374,0.0001189573,0.00004460099,0.0006007168,0.00002574686,0.9963809,0.000039138,0.0001231463,0.0002392744],"study_design_scores_gemma":[0.001103005,0.00002825583,0.0006833158,0.0003885632,0.00007748898,0.0005564899,0.001880197,0.00001613346,0.9933846,0.0008504204,0.0008162705,0.0002152684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936123,0.0003638318,0.0001691772,0.0001748575,0.00005371783,0.00004758908,0.00005273791,0.000007434784,0.005518313],"genre_scores_gemma":[0.9974535,0.00001791043,0.002283865,0.00001559366,0.0000661516,0.000001309352,0.00001188724,0.00004175631,0.0001080027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00541031,"threshold_uncertainty_score":0.9996831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02464573904505814,"score_gpt":0.231764470835317,"score_spread":0.2071187317902589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}