{"id":"W2150584794","doi":"10.1158/1078-0432.ccr-06-2788","title":"Molecular Characterization of Waldenstrom's Macroglobulinemia Reveals Frequent Occurrence of Two B-Cell Clones Having Distinct IgH VDJ Sequences","year":2007,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"clone (Java method); Biology; Bone marrow; Somatic cell; Macroglobulinemia; Germline; Waldenstrom macroglobulinemia; B cell; Germline mutation; Antibody; Immunology; Genetics; Mutation; Gene; Lymphoma; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001354666,0.0002189829,0.0001480842,0.0006699915,0.0001312599,0.0001878067,0.0001422726,0.0002157266,0.0007337914],"category_scores_gemma":[0.0003690202,0.0001050282,0.00009130852,0.0002225761,0.0001551231,0.0001098104,0.000148431,0.0001198509,0.0001400157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222429,"about_ca_system_score_gemma":0.00007862496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002227612,"about_ca_topic_score_gemma":0.0004026731,"domain_scores_codex":[0.999912,0.00001035954,0.00001100998,0.00002196062,0.00002440105,0.00002020926],"domain_scores_gemma":[0.9998889,0.00002437611,0.00003415669,0.00001286937,0.00001233005,0.00002741313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004681156,0.00007117063,0.3175884,0.00007866459,0.00004821817,0.003276999,0.0001879162,0.0001689162,0.6647475,0.0001361218,0.00008808655,0.01313992],"study_design_scores_gemma":[0.00006740382,0.0007608752,0.8309955,0.00001458153,0.0001018953,0.03766719,0.0002250146,0.001498677,0.1269414,0.0001778402,0.001539558,0.00001012557],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997004,0.00009256409,0.0001027339,0.000003084145,5.714249e-7,0.000002477713,0.00001566109,0.000003124359,0.00007936991],"genre_scores_gemma":[0.9995709,0.0000388687,0.000260608,0.000004101641,0.000002318924,0.00000445771,0.00006660291,0.000001190844,0.00005101716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007337914,"threshold_uncertainty_score":0.002454758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1310346231487295,"score_gpt":0.5109195788758971,"score_spread":0.3798849557271676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}