{"id":"W2150605374","doi":"10.1111/pcmr.12435","title":"Iris pigmentation as a quantitative trait: variation in populations of European, East Asian and South Asian ancestry and association with candidate gene polymorphisms","year":2015,"lang":"en","type":"article","venue":"Pigment Cell & Melanoma Research","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Genetics; Candidate gene; Quantitative trait locus; IRIS (biosensor); Trait; Genetic association; East Asia; Evolutionary biology; Gene; Genotype; Single-nucleotide polymorphism; Geography; China","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008420841,0.0002390414,0.0002371355,0.0007253627,0.0002025064,0.0004214983,0.0001364262,0.0002164615,0.001550377],"category_scores_gemma":[0.001210873,0.0001010615,0.0002955398,0.0009219078,0.0003660893,0.0001666717,0.0003458678,0.0002501639,0.0001535987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001219169,"about_ca_system_score_gemma":0.00007531102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001058828,"about_ca_topic_score_gemma":0.00155083,"domain_scores_codex":[0.9996619,0.0001040896,0.00003254812,0.000108774,0.00007272048,0.00001994505],"domain_scores_gemma":[0.99929,0.0002152377,0.0002734222,0.0001090837,0.0000565995,0.00005572716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008392173,0.00007972133,0.8756095,0.00007920315,0.0006244871,0.0002293564,0.0006955253,0.0004432062,0.1030504,0.0003334261,0.00008980047,0.01792614],"study_design_scores_gemma":[0.000005639455,0.00004875023,0.9971354,0.000003076983,0.00004992839,0.0003465691,0.00007116749,0.0003444524,0.001749003,0.00007150944,0.0001697854,0.000004807273],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972401,0.0002003869,0.001789171,0.00001635855,0.00000329922,0.000007113232,0.0001240276,0.000010809,0.0006087653],"genre_scores_gemma":[0.9982643,0.00006310333,0.001288766,0.00001222773,0.000003559581,0.000009844547,0.0001098542,0.000008795591,0.0002395883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001550377,"threshold_uncertainty_score":0.005186498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07037238741399923,"score_gpt":0.3366438079719201,"score_spread":0.2662714205579209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}