{"id":"W2150607482","doi":"10.1093/hmg/ddm264","title":"Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice","year":2007,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Eye Institute","keywords":"Fibulin; Macular degeneration; Biology; Phenotype; Extracellular matrix; Connective tissue; Degeneration (medical); Pathology; Genetics; Gene; Medicine; Ophthalmology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003931428,0.001018342,0.0004041416,0.001230993,0.0002954417,0.0003136057,0.0004676266,0.001250156,0.002131635],"category_scores_gemma":[0.0004088742,0.0005322955,0.000578291,0.0002489371,0.0004793132,0.000351604,0.0004634164,0.0008983591,0.0005586924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003966748,"about_ca_system_score_gemma":0.0002530543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006522419,"about_ca_topic_score_gemma":0.0009529364,"domain_scores_codex":[0.9995686,0.00007142108,0.0000686275,0.0001075607,0.00009408891,0.00008955751],"domain_scores_gemma":[0.9992927,0.0001411868,0.0002936717,0.00006382968,0.00003404847,0.0001744743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004002757,0.000128714,0.0007659103,0.00006837547,0.00002604975,0.0008930507,0.00004829363,0.0001338355,0.9953927,0.0002999545,0.0001149996,0.00172785],"study_design_scores_gemma":[0.0004588196,0.002291079,0.04541687,0.00009914526,0.0001636683,0.01100078,0.0001408868,0.002751989,0.930629,0.0005596775,0.006437913,0.00005018317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933851,0.001224344,0.002584753,0.0001841345,0.00004416021,0.00006798041,0.0009385194,0.0003008702,0.001270104],"genre_scores_gemma":[0.9883106,0.001074156,0.00372565,0.0002485209,0.00003109035,0.0001631067,0.001248901,0.0001282732,0.005069722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002131635,"threshold_uncertainty_score":0.00713104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0327650591017938,"score_gpt":0.3359004515740431,"score_spread":0.3031353924722493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}