{"id":"W2150662349","doi":"10.1021/ja110733q","title":"Three <i>Streptococcus pneumoniae</i> Sialidases: Three Different Products","year":2011,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"BioCryst","keywords":"Sialidase; Chemistry; Glycoconjugate; Streptococcus pneumoniae; Microbiology; Sialic acid; Pathogen; Enzyme; Anomer; Glycan; Human pathogen; Biochemistry; Virology; Antibiotics; Glycoprotein; Neuraminidase; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001572288,0.0002002094,0.0005162993,0.00002146006,0.0001165372,0.00001501566,0.0003233128,0.00006644098,0.00003517943],"category_scores_gemma":[0.000156213,0.0001057366,0.0008404223,0.000377307,0.0005986808,0.0000646642,0.0001190154,0.0007138217,0.000007115138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00015943,"about_ca_system_score_gemma":0.0001640413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000213297,"about_ca_topic_score_gemma":0.000003252531,"domain_scores_codex":[0.9986175,0.00002852458,0.0004577328,0.0001827236,0.0004230734,0.0002904664],"domain_scores_gemma":[0.9983853,0.00005676256,0.0006878854,0.0004267669,0.0002305229,0.0002127243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000407429,0.0003929373,0.1974968,0.00002552642,0.0002318114,0.00000992995,0.0002188283,4.243997e-7,0.7948045,0.00001115048,0.005218455,0.001548859],"study_design_scores_gemma":[0.001458624,0.0009446684,0.2919175,0.0002153375,0.0007355588,0.0008911685,0.0004528572,0.00003264866,0.6931268,0.0009206415,0.008974275,0.0003299493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943334,0.00006543787,0.0001868583,0.004502373,0.0003018292,0.0002276446,0.000004520082,0.00002963522,0.0003482628],"genre_scores_gemma":[0.9966866,0.0000419941,0.0003406776,0.002178844,0.0006859999,0.000009048921,4.823771e-7,0.00002497547,0.00003139625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1016777,"threshold_uncertainty_score":0.4311812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02836110763291639,"score_gpt":0.260900285907282,"score_spread":0.2325391782743657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}