{"id":"W2150705064","doi":"10.1186/1758-3284-3-11","title":"The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck","year":2011,"lang":"en","type":"article","venue":"Head & Neck Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Pfizer Canada; Pfizer","keywords":"Erlotinib; Medicine; Epidermal growth factor receptor; EGFR inhibitors; Oncology; Cancer research; Immunohistochemistry; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009992362,0.0002708435,0.0008812232,0.0001029167,0.0002460883,0.00001203034,0.0001247984,0.0001519439,0.00003789703],"category_scores_gemma":[0.0004720532,0.0001492874,0.00005981639,0.0004281322,0.0001863889,0.00006439586,0.0001739775,0.0003577425,0.000008006612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007333246,"about_ca_system_score_gemma":0.0005208656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001194165,"about_ca_topic_score_gemma":0.003717017,"domain_scores_codex":[0.9974021,0.0006338944,0.0006467279,0.0004137378,0.0003808494,0.0005227411],"domain_scores_gemma":[0.9977962,0.001087242,0.0003326342,0.0003465375,0.0002288793,0.000208492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01185788,0.0005629206,0.9683731,0.00008284854,0.00008879573,0.00004131769,0.008077524,4.53758e-7,0.0001687172,0.00001794374,0.001856381,0.008872145],"study_design_scores_gemma":[0.01040993,0.01007314,0.968875,0.0001293209,0.0002810663,0.00001890497,0.0005636415,0.000005118757,0.00135922,0.00002780494,0.00808275,0.000174089],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994681,0.0004949761,0.000004762029,0.001704062,0.0003400295,0.001398439,0.00004868775,0.00001566658,0.001312402],"genre_scores_gemma":[0.997899,0.00007941436,0.0008206262,0.0005448316,0.00008663515,0.0001131018,0.000007693705,0.00003075294,0.0004179616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009510221,"threshold_uncertainty_score":0.6087763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02876058298546944,"score_gpt":0.3004235876969513,"score_spread":0.2716630047114818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}