{"id":"W2150716328","doi":"10.1111/vox.12292","title":"<scp>HNA</scp> antibody‐mediated neutrophil aggregation is dependent on serine protease activity","year":2015,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Universität Greifswald; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Proteases; Chemistry; Serine; Antibody; Biochemistry; Serine protease; Neutrophil extracellular traps; Iodoacetamide; Elastase; Tosyl; Chymotrypsin; Trypsin; Protease; Enzyme; Cysteine; Immunology; Inflammation; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009880948,0.0002189675,0.0001600765,0.00005101804,0.00007001313,0.00003262616,0.0001339855,0.0001710375,0.00001082998],"category_scores_gemma":[0.0001945174,0.0001955421,0.00008485178,0.0001142794,0.00004038912,0.000007528399,0.00008023775,0.00009124337,0.0001428548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002172938,"about_ca_system_score_gemma":0.00009500993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001911295,"about_ca_topic_score_gemma":0.000042528,"domain_scores_codex":[0.998868,0.0000613728,0.0001487974,0.0004223218,0.0002251496,0.0002743096],"domain_scores_gemma":[0.9991489,0.00001195293,0.0001149288,0.0004182471,0.0001027203,0.0002032506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009684474,0.00634297,0.1692232,0.0001387034,0.001202773,0.0003602743,0.001123648,0.0001772004,0.6533937,0.0001267711,0.08504212,0.08190013],"study_design_scores_gemma":[0.004446839,0.001979327,0.02079084,0.00002636938,0.00008084335,0.00002315762,0.0001240009,0.0001050428,0.8891946,0.0001774102,0.08282939,0.0002221522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940465,0.0005914783,0.00008157858,0.0002760046,0.0001772001,0.0003992025,0.0001086905,0.00003551665,0.004283802],"genre_scores_gemma":[0.9972813,0.0001253076,0.0001327642,0.0005158329,0.0001947984,0.00005753083,0.0003956197,0.00003273138,0.001264169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2358009,"threshold_uncertainty_score":0.7973976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611822716572246,"score_gpt":0.2708012247352176,"score_spread":0.2546829975694951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}