{"id":"W2150716328","doi":"10.1111/vox.12292","title":"<scp>HNA</scp> antibody‐mediated neutrophil aggregation is dependent on serine protease activity","year":2015,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Universität Greifswald; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Proteases; Chemistry; Serine; Antibody; Biochemistry; Serine protease; Neutrophil extracellular traps; Iodoacetamide; Elastase; Tosyl; Chymotrypsin; Trypsin; Protease; Enzyme; Cysteine; Immunology; Inflammation; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001716118,0.0003389425,0.0001804107,0.0001228983,0.00009727983,0.0001733898,0.0001613555,0.0002208968,0.002300071],"category_scores_gemma":[0.00015583,0.00006649098,0.000263602,0.0001103773,0.0001929915,0.0001109533,0.0001182634,0.0003307816,0.0005635174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002623629,"about_ca_system_score_gemma":0.0001761808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005295373,"about_ca_topic_score_gemma":0.0006379632,"domain_scores_codex":[0.9998056,0.00003384623,0.00002339709,0.00003634389,0.00005865402,0.00004222145],"domain_scores_gemma":[0.9998529,0.00002240226,0.00006485944,0.00001686975,0.00002405122,0.00001884104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002017792,0.0000229721,0.0003697009,0.00006243231,0.00001062348,0.000116712,0.000004533862,0.00001919662,0.998094,0.00004072696,0.0001130492,0.0009443551],"study_design_scores_gemma":[0.0000276664,0.0003885985,0.01919892,0.00001256053,0.00002107189,0.001436738,0.00001164359,0.0005417353,0.975501,0.0000378152,0.002818459,0.000003752283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888176,0.003587749,0.003222133,0.0001726289,0.00005003012,0.00006798706,0.0006173936,0.000118715,0.003345783],"genre_scores_gemma":[0.9946119,0.0008938402,0.001739573,0.0001237727,0.00003288814,0.0000447396,0.0009791921,0.00001443929,0.001559754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002300071,"threshold_uncertainty_score":0.007694542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611822716572246,"score_gpt":0.2708012247352176,"score_spread":0.2546829975694951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}