{"id":"W2150783921","doi":"10.4049/jimmunol.0900843","title":"Selectively Reduced Intracellular Proliferation of <i>Salmonella enterica</i> Serovar Typhimurium within APCs Limits Antigen Presentation and Development of a Rapid CD8 T Cell Response","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia; Institute for Biological Sciences","funders":"Canadian Institutes of Health Research","keywords":"Salmonella enterica; Biology; Intracellular; Microbiology; Intracellular parasite; Antigen presentation; CD8; T cell; Cytotoxic T cell; Virulence; Immune system; Salmonella; Cell biology; Immunology; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001569144,0.0004321733,0.0003961675,0.0001335735,0.00007679343,0.00036795,0.0002026495,0.0003278727,0.0009655433],"category_scores_gemma":[0.0001148214,0.0001746091,0.0002096593,0.00008117157,0.0002592952,0.0001674569,0.0002024635,0.0006192659,0.0005494281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002091272,"about_ca_system_score_gemma":0.0002199144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000307368,"about_ca_topic_score_gemma":0.0004593729,"domain_scores_codex":[0.9997265,0.00004314968,0.00002762443,0.00005551763,0.00005465462,0.00009243823],"domain_scores_gemma":[0.9997597,0.00005229897,0.00006722779,0.00002744537,0.00002772456,0.00006558991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009593686,0.00001762506,0.00008245946,0.00002083906,0.000001466802,0.00001174873,0.000003847816,0.00001905854,0.9994044,0.0000296359,0.00001524829,0.0002977683],"study_design_scores_gemma":[0.00001548282,0.0007746678,0.001880307,0.00000507177,0.00001391893,0.0001488604,0.00001198459,0.0004275109,0.9955103,0.00001469846,0.001194333,0.000002916756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958295,0.0008253318,0.001523726,0.00006244109,0.00002958475,0.00001953594,0.0001531077,0.0001064188,0.001450461],"genre_scores_gemma":[0.9951,0.0005767273,0.001760312,0.00005931922,0.00002408086,0.00004399377,0.0004465583,0.0000368148,0.001952173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009655433,"threshold_uncertainty_score":0.003230035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379974408018208,"score_gpt":0.2382942936039099,"score_spread":0.2244945495237279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}