{"id":"W2150783921","doi":"10.4049/jimmunol.0900843","title":"Selectively Reduced Intracellular Proliferation of <i>Salmonella enterica</i> Serovar Typhimurium within APCs Limits Antigen Presentation and Development of a Rapid CD8 T Cell Response","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia; Institute for Biological Sciences","funders":"Canadian Institutes of Health Research","keywords":"Salmonella enterica; Biology; Intracellular; Microbiology; Intracellular parasite; Antigen presentation; CD8; T cell; Cytotoxic T cell; Virulence; Immune system; Salmonella; Cell biology; Immunology; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001964674,0.0002082108,0.0005210439,0.0002863677,0.0001802662,0.000008517475,0.0003409179,0.0002320877,0.00003737579],"category_scores_gemma":[0.0001961904,0.0001499649,0.0000813404,0.0002194183,0.0003358792,0.000162797,0.00004076438,0.0004264591,0.000007446995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004388693,"about_ca_system_score_gemma":0.0003852887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007499597,"about_ca_topic_score_gemma":7.844033e-7,"domain_scores_codex":[0.9965574,0.001851529,0.001115908,0.0001359425,0.0000827103,0.0002564878],"domain_scores_gemma":[0.9975315,0.0004346389,0.00137369,0.0002431291,0.000402713,0.00001437041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03475907,0.0003424303,0.0001402254,0.00001701442,0.0004429512,0.000002861174,0.01294297,0.00002611258,0.9441419,0.00002009574,0.00007725044,0.007087179],"study_design_scores_gemma":[0.002373654,0.00323103,0.02796523,0.0000730603,0.00006510106,0.0005485617,0.00143438,0.0000046085,0.9631526,0.00005620898,0.0009669669,0.0001286381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975297,0.02286438,0.0007805308,0.0004023252,0.0003052485,0.0003000514,0.000003201185,0.00001028159,0.00003697593],"genre_scores_gemma":[0.9966507,0.001986032,0.0009941106,0.00006665552,0.00001541083,0.000002701094,0.000007062341,0.00001505761,0.0002623002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03238542,"threshold_uncertainty_score":0.6115391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379974408018208,"score_gpt":0.2382942936039099,"score_spread":0.2244945495237279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}