{"id":"W2150801544","doi":"10.1210/mend.16.7.0875","title":"Synergistic Action of Prolactin (PRL) and Androgen on PRL-Inducible Protein Gene Expression in Human Breast Cancer Cells: A Unique Model for Functional Cooperation between Signal Transducer and Activator of Transcription-5 and Androgen Receptor","year":2002,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canada Research Chairs; Université Laval","keywords":"Androgen receptor; STAT5; Biology; Prolactin receptor; STAT protein; Dihydrotestosterone; Reporter gene; Activator (genetics); Androgen; Transcription factor; Molecular biology; Cell biology; Prolactin; Phosphorylation; Receptor; Gene expression; Gene; STAT3; Endocrinology; Hormone; Biochemistry; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007393098,0.0001820368,0.0002488605,0.0001103409,0.00007081375,0.000007726145,0.00004632787,0.0002387547,0.00001128171],"category_scores_gemma":[0.000008288673,0.000171486,0.00004654504,0.00006596293,0.0001080717,0.00001417112,0.00002035833,0.0001389188,1.182062e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001843464,"about_ca_system_score_gemma":0.00003415551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002184777,"about_ca_topic_score_gemma":0.00001032378,"domain_scores_codex":[0.998933,0.0001158648,0.0002535905,0.0004028263,0.00008462917,0.0002101375],"domain_scores_gemma":[0.9996257,0.00001427229,0.0001022089,0.0001238611,0.00006739878,0.00006651579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006149253,0.0001299025,0.0005841414,0.000131894,0.00008911444,0.00000232102,0.0001157458,0.0006816766,0.9954751,0.00009081023,0.0000180565,0.002066301],"study_design_scores_gemma":[0.001843389,0.0006627237,0.0003515441,0.0000597996,0.00005695407,0.00002094834,0.00002089318,0.002060416,0.9946818,0.00004609804,0.00003780904,0.0001576734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908313,0.001101747,0.007021392,0.0001072787,0.00002125381,0.0007816007,0.0001162069,0.000007542596,0.00001172458],"genre_scores_gemma":[0.9987626,0.0003210682,0.0004919932,0.00001806688,0.00003550304,0.0002154837,0.00008696514,0.00002597068,0.00004231323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007931382,"threshold_uncertainty_score":0.6992998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02294577444282253,"score_gpt":0.2525420755331934,"score_spread":0.2295963010903709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}