{"id":"W2150801544","doi":"10.1210/mend.16.7.0875","title":"Synergistic Action of Prolactin (PRL) and Androgen on PRL-Inducible Protein Gene Expression in Human Breast Cancer Cells: A Unique Model for Functional Cooperation between Signal Transducer and Activator of Transcription-5 and Androgen Receptor","year":2002,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canada Research Chairs; Université Laval","keywords":"Androgen receptor; STAT5; Biology; Prolactin receptor; STAT protein; Dihydrotestosterone; Reporter gene; Activator (genetics); Androgen; Transcription factor; Molecular biology; Cell biology; Prolactin; Phosphorylation; Receptor; Gene expression; Gene; STAT3; Endocrinology; Hormone; Biochemistry; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001910003,0.0002673719,0.0003219091,0.0001812535,0.0001304811,0.000264849,0.0002135825,0.0001985483,0.0008626686],"category_scores_gemma":[0.00008632619,0.0001694445,0.000420265,0.0002645699,0.0001494568,0.0001142365,0.0002251023,0.0003974472,0.0003602494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003103323,"about_ca_system_score_gemma":0.0002225201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009626645,"about_ca_topic_score_gemma":0.00139555,"domain_scores_codex":[0.9996971,0.00008364514,0.00002508275,0.0000496175,0.00007933211,0.00006525146],"domain_scores_gemma":[0.9999436,0.00001682298,0.00001136246,0.000008887962,0.0000064389,0.00001292004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001902242,0.00003562636,0.0002036472,0.00003884018,0.000004943445,0.00006547542,0.0000169496,0.00007447872,0.9983013,0.0000778861,0.00005188649,0.0009387508],"study_design_scores_gemma":[0.00005036513,0.000673637,0.004557161,0.000005289429,0.00003052833,0.0004461278,0.00004797553,0.002951062,0.9877251,0.00004801833,0.0034557,0.00000894869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890464,0.003013899,0.005427432,0.0002045181,0.00006795729,0.00005146237,0.0005519814,0.00009559315,0.00154084],"genre_scores_gemma":[0.9918355,0.0009967904,0.005092982,0.0000668498,0.00001501831,0.00004389794,0.0006528989,0.00001237116,0.001283684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009626645,"threshold_uncertainty_score":0.002885878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02294577444282253,"score_gpt":0.2525420755331934,"score_spread":0.2295963010903709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}