{"id":"W2150844644","doi":"10.1124/mol.109.061069","title":"The Small GTPase Ral Couples the Angiotensin II Type 1 Receptor to the Activation of Phospholipase C-δ1","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Phospholipase C; Angiotensin II; Small GTPase; GTP'; Receptor; Cell biology; Small interfering RNA; Endocytosis; Gq alpha subunit; Intracellular; Inositol phosphate; GTPase; Guanine nucleotide exchange factor; Chemistry; Biology; Signal transduction; Inositol; G protein; Biochemistry; RNA; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002691608,0.0004053691,0.0002581915,0.0005766461,0.0003490236,0.0007930011,0.0003730182,0.000300645,0.0008182902],"category_scores_gemma":[0.0004014295,0.0001945488,0.0002881528,0.0002706572,0.0006636258,0.0003615104,0.0004398597,0.001001385,0.0007967819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009319368,"about_ca_system_score_gemma":0.0003848348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001029519,"about_ca_topic_score_gemma":0.001398867,"domain_scores_codex":[0.9997924,0.00003924176,0.000008667615,0.00004036256,0.00005869739,0.00006069867],"domain_scores_gemma":[0.9998894,0.00002907269,0.00002489047,0.00001168859,0.00001677503,0.00002812291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000358693,0.00002862259,0.0004849448,0.0001171974,0.00001314508,0.0003167052,0.000042856,0.0003615306,0.9795908,0.00519563,0.000392624,0.01309713],"study_design_scores_gemma":[0.00005223424,0.0001884825,0.005501318,0.0000161242,0.00002831111,0.0008687245,0.00009007331,0.001661156,0.9749118,0.001386034,0.01527687,0.00001885383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8903346,0.04215382,0.03700273,0.00455148,0.0006367555,0.00008923678,0.0005628525,0.001059874,0.02360864],"genre_scores_gemma":[0.9770204,0.01201232,0.004165166,0.0002898852,0.0001386495,0.00002265536,0.0002438895,0.00004855938,0.006058559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001029519,"threshold_uncertainty_score":0.00676167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01189037352185816,"score_gpt":0.2680764282072661,"score_spread":0.2561860546854079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}