{"id":"W2150853463","doi":"10.1242/bio.20134267","title":"Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain","year":2013,"lang":"en","type":"article","venue":"Biology Open","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; Biology; Synaptic vesicle; Scaffold protein; Synaptosome; Cell biology; Active zone; Fusion protein; Biophysics; Vesicle; Biochemistry; Membrane; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222179,0.0002626116,0.0001904571,0.0001350069,0.0002267063,0.0004140871,0.000369256,0.0002397454,0.0008107974],"category_scores_gemma":[0.0001660579,0.0001511904,0.0001962302,0.0001287317,0.0002243163,0.0003297403,0.0004289637,0.0005311511,0.0004400575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005076932,"about_ca_system_score_gemma":0.0002094068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007638001,"about_ca_topic_score_gemma":0.001158274,"domain_scores_codex":[0.9998758,0.00001168625,0.000008018133,0.00003619666,0.00003645475,0.00003184744],"domain_scores_gemma":[0.9999343,0.000009533264,0.00001693697,0.00001147678,0.00001054924,0.00001724563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000666524,0.00001460977,0.0002107367,0.00001983612,0.000003600233,0.00005080439,0.00001120813,0.0001579424,0.9985417,0.0002266256,0.00005036501,0.0006458749],"study_design_scores_gemma":[0.00002501367,0.00007031796,0.003432711,0.000003339545,0.00001076933,0.0001760799,0.00002683166,0.006130444,0.9881391,0.00007156726,0.001906491,0.000007481629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939755,0.0002490586,0.004309199,0.00007795182,0.00001133087,0.00001688908,0.0001194861,0.00007031454,0.001170233],"genre_scores_gemma":[0.9964977,0.0001379274,0.001918887,0.00004053552,0.000004411634,0.00001652289,0.0002128283,0.00001097377,0.001160248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008107974,"threshold_uncertainty_score":0.003683627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241034896364755,"score_gpt":0.2484414255638407,"score_spread":0.2360310766001932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}