{"id":"W2150900509","doi":"10.1242/jcs.123430","title":"A gap junction docking mechanism revealed by functional rescue of a human disease-linked connexin mutant","year":2013,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Docking (animal); Connexin; Mutant; Mechanism (biology); Gap junction; Cell biology; Computational biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007161222,0.0003557519,0.000189129,0.0001038223,0.0001257872,0.0001020254,0.0001995159,0.0002890759,0.0008560495],"category_scores_gemma":[0.0000998444,0.0001091156,0.0002479228,0.00007672389,0.0001827011,0.0001002642,0.0001967699,0.0003515113,0.0002737222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222123,"about_ca_system_score_gemma":0.0001167852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005575526,"about_ca_topic_score_gemma":0.000317527,"domain_scores_codex":[0.9999331,0.00001195429,0.00000845552,0.00001724137,0.0000163966,0.00001279189],"domain_scores_gemma":[0.9999493,0.000006455501,0.00001473544,0.000008731027,0.000003709441,0.00001704077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000764488,0.00001782342,0.0001495678,0.00001389903,0.000005567901,0.0001857698,0.0000092164,0.0002693373,0.9985784,0.0001360444,0.00002134816,0.0005366213],"study_design_scores_gemma":[0.00003079626,0.0004514726,0.005161307,0.000006409692,0.00002849832,0.001385569,0.00002758964,0.005538212,0.9858546,0.0001325232,0.001371102,0.00001193177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974121,0.0001699541,0.001894663,0.00001970719,0.0000110327,0.000008750968,0.0001125271,0.00003562516,0.0003356235],"genre_scores_gemma":[0.9980148,0.00009307986,0.001136987,0.0000124284,0.000001313221,0.000008088596,0.000180322,0.000009552971,0.0005434918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008560495,"threshold_uncertainty_score":0.002863765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01512317142109533,"score_gpt":0.2439124202286869,"score_spread":0.2287892488075916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}