{"id":"W2150907474","doi":"10.1139/v10-002","title":"Microwave-assisted, palladium-catalyzed carbonylative cyclization — Rapid synthesis of 2-quinolones from unprotected 2-iodoanilines and terminal alkynes","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Catalysis; Palladium; Carbonylation; Carbon monoxide; Microwave irradiation; Molybdenum; Organic chemistry; Combinatorial chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002252715,0.0001983071,0.0004044403,0.00006179728,0.00009084654,0.00004454102,0.0002578293,0.0003493401,0.001647048],"category_scores_gemma":[0.001733154,0.0001633578,0.0001253164,0.0001064712,0.0002956543,0.00008352168,0.00001696499,0.0003128747,0.00000125339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005433816,"about_ca_system_score_gemma":0.0004783451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001351842,"about_ca_topic_score_gemma":0.002817549,"domain_scores_codex":[0.9987874,0.00003143307,0.0005745402,0.0002116608,0.0001792876,0.0002156969],"domain_scores_gemma":[0.9981127,0.0003239446,0.0006413202,0.0002101636,0.0003677218,0.0003440944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005849208,0.00002045902,0.008925074,0.00008035194,0.00008419244,0.00002796708,0.0001483143,0.000001082111,0.9641314,0.00000143326,0.00003269721,0.0264885],"study_design_scores_gemma":[0.0003607768,0.00001176727,0.01718757,0.0002059046,0.000110313,0.0001585892,0.0003804541,0.00005920451,0.9807912,0.0001827584,0.0003680972,0.0001833558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974515,0.000694543,0.00001392131,0.0001989634,0.00008913583,0.00003983751,0.0001364324,0.000008385662,0.00136725],"genre_scores_gemma":[0.9988314,0.00005220411,0.0006403775,0.0000145565,0.0003536142,0.000004879783,0.00003905202,0.00001602968,0.00004789066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02630515,"threshold_uncertainty_score":0.9992656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01621920119194009,"score_gpt":0.2212488745461131,"score_spread":0.205029673354173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}