{"id":"W2150917095","doi":"10.1038/msb4100037","title":"Physics takes another stab at biological design principles","year":2005,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biology; Stab; Computational biology; Engineering ethics; Engineering; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000400602,0.0003493654,0.0004184995,0.00005421954,0.0001283605,0.000026213,0.0003822036,0.000472232,0.00004280429],"category_scores_gemma":[0.00005053813,0.000290926,0.0002449594,0.0001605603,0.0002039994,0.00000318064,0.000189235,0.00009497664,0.0001394244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006960944,"about_ca_system_score_gemma":0.00005993915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000164062,"about_ca_topic_score_gemma":0.00001873973,"domain_scores_codex":[0.9975056,0.0006245443,0.0004254624,0.0007598038,0.0001262641,0.0005583048],"domain_scores_gemma":[0.9987852,0.00002172269,0.0002078453,0.0007667952,0.0001055989,0.0001128391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006255952,0.00006347728,0.005022956,0.00001016689,0.000280211,0.000008310911,0.00002014455,0.01888927,0.9717567,0.0009511622,0.001366055,0.001568969],"study_design_scores_gemma":[0.0007253369,0.0005012025,0.000773273,0.00001532265,0.00007534373,0.00008524794,0.00003291157,0.004631167,0.5257168,0.00005277298,0.4666832,0.0007073279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7012051,0.01188496,0.2846797,0.0001506536,0.0002475579,0.0005029694,0.00002589442,0.00006850691,0.001234668],"genre_scores_gemma":[0.9938465,0.0001436591,0.003064802,0.000385074,0.0007457164,0.00009129994,0.0002095062,0.00005334473,0.001460145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4653172,"threshold_uncertainty_score":0.9999543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0359091748748492,"score_gpt":0.2469029728514839,"score_spread":0.2109937979766346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}