{"id":"W2150930870","doi":"10.1158/0008-5472.can-08-1833","title":"IκB Kinase-α Regulates Endothelial Cell Motility and Tumor Angiogenesis","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health","keywords":"Angiogenesis; Cancer research; Endothelial stem cell; Metastasis; Vascular endothelial growth inhibitor; Vascular endothelial growth factor B; Biology; Motility; Vascular endothelial growth factor A; Cell growth; Cell biology; Vascular endothelial growth factor; Medicine; Internal medicine; Cancer; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001590344,0.0003978202,0.000150298,0.0002247956,0.0001951262,0.0003445491,0.0001755744,0.0001542391,0.0007972855],"category_scores_gemma":[0.000183453,0.0001132748,0.000131078,0.0001726153,0.0002884073,0.0002321218,0.0001634834,0.0003669761,0.000509291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004343901,"about_ca_system_score_gemma":0.0002314195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000626929,"about_ca_topic_score_gemma":0.0005993645,"domain_scores_codex":[0.9999051,0.00001681435,0.000004771111,0.00002003077,0.0000244023,0.00002878197],"domain_scores_gemma":[0.9999124,0.000005345143,0.00003599371,0.000005195598,0.00001296371,0.00002804926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000338646,0.00006431802,0.001623119,0.0001716649,0.00001448215,0.0002765844,0.00004221515,0.0003070982,0.9804915,0.000703798,0.0005708296,0.01539572],"study_design_scores_gemma":[0.000188872,0.0009188516,0.1072696,0.00009512626,0.0001060897,0.003097096,0.0003291364,0.004611001,0.8246284,0.003419048,0.05529761,0.0000392695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8776854,0.09233593,0.01390924,0.001015174,0.0003056738,0.00005393011,0.0005169469,0.000494026,0.01368365],"genre_scores_gemma":[0.9779885,0.01668826,0.00124883,0.00007568011,0.00005412741,0.00002053207,0.0001660048,0.00001608499,0.003742008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007972855,"threshold_uncertainty_score":0.003151715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05781048350100963,"score_gpt":0.3305616058780622,"score_spread":0.2727511223770526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}