{"id":"W2150982562","doi":"10.1203/pdr.0b013e31819e4305","title":"Initial Validation of a Novel Protein Biomarker Panel for Active Pediatric Lupus Nephritis","year":2009,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Toronto","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Lupus Research Alliance; U.S. Department of Defense","keywords":"Lupus nephritis; Ceruloplasmin; Urinary system; Albumin; Biomarker; Transferrin; Medicine; Internal medicine; Hemopexin; Blood proteins; Urine; Nephritis; Immunology; Endocrinology; Gastroenterology; Chemistry; Biochemistry; Disease; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003385741,0.0008274765,0.0006154695,0.001478107,0.0006714371,0.0008139449,0.0006303234,0.0008913102,0.001203726],"category_scores_gemma":[0.006829645,0.0002849887,0.0004293359,0.0006840361,0.0005565695,0.0005837214,0.00058671,0.001010377,0.000583707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006466324,"about_ca_system_score_gemma":0.0006245399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148795,"about_ca_topic_score_gemma":0.001796731,"domain_scores_codex":[0.9971781,0.0007700682,0.0002595494,0.0004946018,0.001031528,0.0002661553],"domain_scores_gemma":[0.9969116,0.001192132,0.000201182,0.0002216601,0.001169348,0.0003040201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003009588,0.002224386,0.4839297,0.0003089967,0.0002550109,0.003468747,0.001366191,0.001363398,0.4279265,0.0007167927,0.005413943,0.07001676],"study_design_scores_gemma":[0.0003859977,0.006715549,0.7127641,0.0001487957,0.0004025475,0.01116868,0.0006747571,0.009135516,0.2340576,0.0006179581,0.023876,0.00005241817],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866905,0.001144164,0.006322613,0.0006532163,0.0001555156,0.0003926825,0.001487757,0.0001229813,0.003030597],"genre_scores_gemma":[0.9888114,0.0002790649,0.007223725,0.0004604791,0.00006171886,0.0002119094,0.002091042,0.00002750106,0.0008331701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003385741,"threshold_uncertainty_score":0.01790571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1784163294067255,"score_gpt":0.4256051313515169,"score_spread":0.2471888019447914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}