{"id":"W2151072136","doi":"10.1038/nature14618","title":"Directional dominance on stature and cognition in diverse human populations","year":2015,"lang":"en","type":"review","venue":"Nature","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre for Global Health Research","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Minority Health and Health Disparities; National Institute on Deafness and Other Communication Disorders; National Center for Advancing Translational Sciences; Wellcome Trust; National Human Genome Research Institute; Pfizer; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; Medical Research Council; Novo Nordisk Fonden; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; National Cancer Institute; British Heart Foundation; Yale University","keywords":"Runs of Homozygosity; Quantitative trait locus; Inbreeding; Biology; Genetics; Dominance (genetics); Disease gene identification; Trait; Inbreeding depression; Population; Demography; Genotype; Phenotype; Single-nucleotide polymorphism; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001323385,0.0009037546,0.00145833,0.001480761,0.0002794994,0.001200898,0.0009065614,0.001427696,0.002237584],"category_scores_gemma":[0.002384499,0.0002864496,0.0004305511,0.002627505,0.001199409,0.0009606919,0.0009916074,0.001565424,0.0003999637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006681685,"about_ca_system_score_gemma":0.001769213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00556008,"about_ca_topic_score_gemma":0.008840391,"domain_scores_codex":[0.9997583,0.00006729376,0.00003622148,0.00005710853,0.00006098689,0.00001998574],"domain_scores_gemma":[0.9989753,0.0007128567,0.000101861,0.00002741549,0.0001321277,0.00005049704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.000130135,0.00005167726,0.00374926,0.01169175,0.0004647938,0.0002293876,0.0001179544,0.0006272022,0.0004619753,0.008391616,0.02576049,0.9483237],"study_design_scores_gemma":[0.00006513132,0.0001430693,0.02963464,0.01742245,0.001392436,0.002127357,0.0003961757,0.0003877309,0.0004313977,0.03504186,0.9128403,0.0001173706],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002675906,0.9982602,0.0001529452,0.0006753083,0.0001431594,0.000001851977,0.00003972156,0.000003534494,0.0004557475],"genre_scores_gemma":[0.001529823,0.9975272,0.0001408414,0.0002410449,0.0003442197,0.000003410031,0.00003364668,8.609674e-7,0.0001789227],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00556008,"threshold_uncertainty_score":0.01105541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05146663733783268,"score_gpt":0.388156115469782,"score_spread":0.3366894781319493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}