{"id":"W2151108285","doi":"10.1101/gad.1787109","title":"Histone H2A.Z is essential for estrogen receptor signaling","year":2009,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Chromatin; Enhancer; Histone; Nucleosome; Regulation of gene expression; Promoter; Estrogen receptor; Cell biology; Gene; ChIA-PET; Gene expression; Estrogen receptor alpha; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001161317,0.0001614981,0.0001296589,0.0000282049,0.0001381532,0.00002516117,0.0001770376,0.0001077004,0.00004065564],"category_scores_gemma":[0.000007792833,0.0001691303,0.00008203591,0.00003910779,0.00001786911,0.00000175723,0.00005238082,0.0000306619,0.00002001387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004425943,"about_ca_system_score_gemma":0.0001824363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001685027,"about_ca_topic_score_gemma":0.00000231847,"domain_scores_codex":[0.9990418,0.000009248239,0.0002509111,0.000323028,0.0001010411,0.0002739913],"domain_scores_gemma":[0.9995617,0.000003378326,0.00008119889,0.0001978035,0.00007983398,0.00007607864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003877539,0.00004749591,0.0001187644,0.00001205491,0.00005345795,5.606627e-7,0.0001604109,0.00008925384,0.952249,0.00008979461,0.002893748,0.04424671],"study_design_scores_gemma":[0.0003514004,0.0001008894,0.000271879,0.000006594458,0.00001224788,0.000004373924,0.00003555016,0.00009443236,0.7753392,0.0001201367,0.223438,0.0002252688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842724,0.001551433,0.01325029,0.0002808948,0.0002264661,0.0002371427,0.00001935778,0.00001435566,0.0001476464],"genre_scores_gemma":[0.8581657,0.000281057,0.1379659,0.0009199448,0.0003916804,0.00005573605,0.000645065,0.00003287091,0.00154204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2205442,"threshold_uncertainty_score":0.6896933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006955520818399136,"score_gpt":0.2436272924636719,"score_spread":0.2366717716452728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}