{"id":"W2151108285","doi":"10.1101/gad.1787109","title":"Histone H2A.Z is essential for estrogen receptor signaling","year":2009,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Chromatin; Enhancer; Histone; Nucleosome; Regulation of gene expression; Promoter; Estrogen receptor; Cell biology; Gene; ChIA-PET; Gene expression; Estrogen receptor alpha; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270591,0.0002566365,0.0002021404,0.0001656611,0.0003263001,0.00043774,0.0002578684,0.0002636384,0.001275064],"category_scores_gemma":[0.0001698403,0.0002145771,0.0002046222,0.0001109312,0.0002522514,0.0002026688,0.0003102633,0.0002500809,0.0009623463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000364219,"about_ca_system_score_gemma":0.0003506806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001344769,"about_ca_topic_score_gemma":0.001557557,"domain_scores_codex":[0.9998896,0.00001075884,0.000007940988,0.00002923819,0.00003338342,0.00002905707],"domain_scores_gemma":[0.9998676,0.00001300773,0.00003212746,0.00001732608,0.00002086761,0.00004901423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213932,0.00001607381,0.001332041,0.00003271023,0.000007066822,0.00009029545,0.00001107939,0.0000652875,0.9946957,0.0002297914,0.00009207154,0.00330648],"study_design_scores_gemma":[0.00003443083,0.0002174533,0.07090229,0.00001259147,0.00002096979,0.0008491769,0.00006056022,0.001021828,0.915097,0.0006416379,0.01112716,0.00001500225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816285,0.004375897,0.007925598,0.0003602089,0.0000928008,0.00002840982,0.0008838313,0.0003521497,0.004352572],"genre_scores_gemma":[0.9949629,0.000688904,0.001502955,0.00004437108,0.00001114581,0.000008250201,0.0004223213,0.00002213137,0.002337059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001344769,"threshold_uncertainty_score":0.004265487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006955520818399136,"score_gpt":0.2436272924636719,"score_spread":0.2366717716452728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}