{"id":"W2151110168","doi":"10.1002/anie.201201447","title":"Turning “On” and “Off” a Pyridoxal 5′‐Phosphate Mimic Using Light","year":2012,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Photochromic and Fluorescence Chemistry","field":"Materials Science","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Racemization; Pyridinium; Pyridoxal; Pyridoxal phosphate; Cofactor; Aldehyde; Chemistry; Pyridoxal 5-Phosphate; Phosphate; Catalysis; Stereochemistry; Combinatorial chemistry; Enzyme; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001209746,0.0002760405,0.0001938931,0.0001191308,0.000205101,0.0003731427,0.0005648577,0.0003323234,0.002231507],"category_scores_gemma":[0.0001904889,0.0002191654,0.0002168722,0.0001238461,0.0003174888,0.0002889043,0.0002306386,0.0003744032,0.0003798414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002911968,"about_ca_system_score_gemma":0.0002578859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005006164,"about_ca_topic_score_gemma":0.0005153288,"domain_scores_codex":[0.9998462,0.00001186964,0.000006943663,0.0000493315,0.00003949133,0.0000462081],"domain_scores_gemma":[0.9999099,0.00002687145,0.00001708961,0.00001441117,0.000007843663,0.00002390842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002335211,0.00002605152,0.0001851597,0.00005193776,0.000005865369,0.0001352777,0.00005849864,0.0001154543,0.9937993,0.001009478,0.0001682076,0.00421119],"study_design_scores_gemma":[0.00002035713,0.0001353907,0.0004632109,0.000003254785,0.000006343031,0.00008405271,0.0000183627,0.0007293165,0.9966898,0.0001275891,0.001714293,0.000008147418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852012,0.0003578093,0.006071407,0.0001436808,0.0000934718,0.00004461338,0.0001238555,0.0003583454,0.007605595],"genre_scores_gemma":[0.9934655,0.0002024735,0.002857228,0.00008090476,0.000008221249,0.0000264399,0.00009085807,0.00003835944,0.003230104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002231507,"threshold_uncertainty_score":0.007465124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01823480827196482,"score_gpt":0.2637263149355485,"score_spread":0.2454915066635837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}