{"id":"W2151141519","doi":"10.1093/carcin/24.1.39","title":"Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice","year":2003,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital","funders":"Canadian Institutes of Health Research; Cancer Research Society","keywords":"DNMT1; DNA methylation; Methyltransferase; Carcinogenesis; Methylation; Endocrinology; Internal medicine; Biology; DNA methyltransferase; Cancer; Molecular biology; Medicine; Gene expression; DNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003285435,0.0008728681,0.0008327331,0.001227075,0.0003115709,0.0005840676,0.0004369078,0.0009321652,0.002142717],"category_scores_gemma":[0.000326935,0.0005026562,0.0005858844,0.0003798382,0.0005915203,0.0004017082,0.0004029064,0.001304089,0.0005817037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007110996,"about_ca_system_score_gemma":0.0005409629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002131307,"about_ca_topic_score_gemma":0.003315106,"domain_scores_codex":[0.9994782,0.00006780928,0.00006305408,0.0001759272,0.0001038249,0.0001112884],"domain_scores_gemma":[0.9987882,0.0001290033,0.0004157063,0.00008171586,0.00005908758,0.0005264481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00181716,0.0001590536,0.0006209361,0.00004407808,0.00002140674,0.00005961984,0.00002415305,0.00008823552,0.9958467,0.00009882918,0.00004659015,0.001173386],"study_design_scores_gemma":[0.0002484182,0.003613664,0.01186708,0.00002612691,0.0001360076,0.0005633267,0.00008858477,0.001170175,0.9793751,0.0001660163,0.002716743,0.00002881483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99571,0.001124354,0.0006745208,0.0001420326,0.00003300531,0.0000403042,0.001367267,0.0001238154,0.000784581],"genre_scores_gemma":[0.9848185,0.001551032,0.003141151,0.000189751,0.00002966626,0.0001430701,0.002009552,0.0001671691,0.007950204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002142717,"threshold_uncertainty_score":0.007168114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009473169638856124,"score_gpt":0.2576006576873801,"score_spread":0.2481274880485239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}