{"id":"W2151168658","doi":"10.1093/molehr/gaq003","title":"Toward gene therapy of premature ovarian failure: intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice","year":2010,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Folliculogenesis; Follicle-stimulating hormone receptor; Biology; Endocrinology; Ovary; Internal medicine; Antral follicle; Follicle-stimulating hormone; Premature ovarian failure; Ovarian follicle; Andrology; Hormone; Embryo; Luteinizing hormone; Medicine; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000320495,0.0004909051,0.0003701873,0.0004773294,0.0001522949,0.0003418359,0.0003164752,0.0005074457,0.001532094],"category_scores_gemma":[0.0001427858,0.0002475581,0.0004397627,0.0001576303,0.0004086683,0.0002753466,0.0002285995,0.0007405565,0.0004881572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002167684,"about_ca_system_score_gemma":0.0002502793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004607563,"about_ca_topic_score_gemma":0.0005611273,"domain_scores_codex":[0.9997777,0.00003359333,0.00002748452,0.00005231757,0.00005480492,0.0000539989],"domain_scores_gemma":[0.9998424,0.00002306078,0.00005487301,0.00002212731,0.00001388104,0.00004372121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001988407,0.00011944,0.000127024,0.00003721577,0.000005668877,0.00007071935,0.00001994862,0.00004872017,0.9976388,0.0001827983,0.00005889476,0.001491893],"study_design_scores_gemma":[0.0001997483,0.002233711,0.001956823,0.00001467963,0.00004080312,0.0005756493,0.00004013193,0.0008007463,0.9889413,0.00006987774,0.005118644,0.000008078975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870561,0.001663501,0.007568537,0.0002460331,0.0001754154,0.0002454889,0.0007434333,0.0002746258,0.00202675],"genre_scores_gemma":[0.9741755,0.002466924,0.01248569,0.0001279089,0.0000480868,0.0003935354,0.001269469,0.00009124863,0.008941548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001532094,"threshold_uncertainty_score":0.005125403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02418629316335631,"score_gpt":0.2840283323741045,"score_spread":0.2598420392107482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}