{"id":"W2151189567","doi":"10.1128/aac.48.8.3112-3118.2004","title":"Omiganan Pentahydrochloride (MBI 226), a Topical 12-Amino-Acid Cationic Peptide: Spectrum of Antimicrobial Activity and Measurements of Bactericidal Activity","year":2004,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Use and Resistance","field":"Immunology and Microbiology","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Antimicrobial; Peptide; Cationic polymerization; Microbiology; Yeast; Biological activity; Bacteria; Chemistry; Biology; In vitro; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001998213,0.0003449502,0.0004471453,0.0002261351,0.0001137488,0.0001609761,0.0001368935,0.000272006,0.0007750327],"category_scores_gemma":[0.0002688601,0.00009114089,0.0001208947,0.0001868673,0.0001816907,0.0001257594,0.000123474,0.0002825188,0.0001633105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868698,"about_ca_system_score_gemma":0.0001923549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005498792,"about_ca_topic_score_gemma":0.00103444,"domain_scores_codex":[0.9997907,0.00005487901,0.00001938288,0.00003316869,0.00006618454,0.000035612],"domain_scores_gemma":[0.9998374,0.00002955226,0.0000524684,0.00001146864,0.0000311893,0.00003788358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003797078,0.00004288068,0.001078346,0.00007112475,0.000005280813,0.00007009662,0.00001302965,0.00003704161,0.9908145,0.00001205024,0.00002004949,0.007455764],"study_design_scores_gemma":[0.00008951334,0.01157293,0.02714323,0.00001263118,0.00003490039,0.002130467,0.00006329197,0.0002163637,0.9571754,0.00002314081,0.001526383,0.00001177558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957305,0.002889734,0.0006737327,0.00002673164,0.00001050596,0.00004078192,0.00009087002,0.000009784497,0.0005273751],"genre_scores_gemma":[0.9954333,0.001469451,0.00212503,0.00002914666,0.00001702207,0.00003021336,0.0001873881,0.000003492325,0.0007049529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007750327,"threshold_uncertainty_score":0.002592742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01689708060758588,"score_gpt":0.2374910726026893,"score_spread":0.2205939919951034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}