{"id":"W2151189567","doi":"10.1128/aac.48.8.3112-3118.2004","title":"Omiganan Pentahydrochloride (MBI 226), a Topical 12-Amino-Acid Cationic Peptide: Spectrum of Antimicrobial Activity and Measurements of Bactericidal Activity","year":2004,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Use and Resistance","field":"Immunology and Microbiology","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Antimicrobial; Peptide; Cationic polymerization; Microbiology; Yeast; Biological activity; Bacteria; Chemistry; Biology; In vitro; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000129701,0.0002817147,0.0005582619,0.00008529481,0.0001774125,0.00002123778,0.0001760542,0.0002444241,0.0001112777],"category_scores_gemma":[0.000009502693,0.0002535888,0.0001289112,0.0001084035,0.0004964118,0.000160299,0.00007994995,0.0002014122,0.000007887517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004560264,"about_ca_system_score_gemma":0.00009076859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027468,"about_ca_topic_score_gemma":0.0003212809,"domain_scores_codex":[0.9987347,0.00006378375,0.0003370967,0.0004284322,0.00007108372,0.0003648791],"domain_scores_gemma":[0.9993294,0.0000182713,0.0002999252,0.0002626881,0.00004613677,0.00004352181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006610591,0.0005972893,0.03669412,0.0001487625,0.0002797143,0.00000302559,0.0004460863,0.000001891918,0.9588174,0.00003275044,0.0005746179,0.001743232],"study_design_scores_gemma":[0.002929331,0.000202069,0.1995448,0.0001211815,0.00005482776,0.00003931812,0.00001464427,9.313003e-7,0.7962879,0.00002307889,0.0005757968,0.0002061532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976408,0.00007880787,0.0002473761,0.001212337,0.0002736453,0.0002963987,0.00004559861,0.00002251095,0.000182478],"genre_scores_gemma":[0.9980628,0.0008146885,0.0001678354,0.0004433397,0.0000449917,0.00000144953,0.00002042682,0.00002422558,0.0004202723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1628507,"threshold_uncertainty_score":0.9999917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01689708060758588,"score_gpt":0.2374910726026893,"score_spread":0.2205939919951034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}