{"id":"W2151212270","doi":"10.1016/j.pbb.2008.09.005","title":"Potential of the rat model of conditioned gaping to detect nausea produced by rolipram, a phosphodiesterase-4 (PDE4) inhibitor","year":2008,"lang":"en","type":"article","venue":"Pharmacology Biochemistry and Behavior","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Rolipram; Context (archaeology); Nausea; Pharmacology; Conditioning; Phosphodiesterase inhibitor; Chemistry; Medicine; Anesthesia; Phosphodiesterase; Internal medicine; Enzyme; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000422697,0.00183206,0.0008531327,0.0007917035,0.0004176702,0.0003375058,0.0006439399,0.0007731023,0.003074671],"category_scores_gemma":[0.0005227303,0.0004391008,0.0006375688,0.0002134318,0.001222933,0.001259899,0.0004992485,0.002803588,0.0005676411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005520852,"about_ca_system_score_gemma":0.001162997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001840041,"about_ca_topic_score_gemma":0.002906687,"domain_scores_codex":[0.999702,0.00005449807,0.00001691934,0.00006839783,0.00005664666,0.0001015103],"domain_scores_gemma":[0.9994289,0.00007759206,0.00009747085,0.00008969336,0.00004432562,0.0002620213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008404222,0.001508019,0.0009769823,0.0001827968,0.00005482094,0.000411889,0.00009136401,0.0002226452,0.9798135,0.0008466309,0.0004421723,0.007045092],"study_design_scores_gemma":[0.0007130796,0.03296667,0.0104285,0.00004619137,0.0003051682,0.001289664,0.0001913268,0.005074453,0.9458523,0.0007204778,0.002346501,0.00006571913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910191,0.001169543,0.004379502,0.0005792429,0.0003015954,0.0001672339,0.0007614887,0.0002088943,0.001413301],"genre_scores_gemma":[0.9858934,0.001549616,0.005717125,0.000278488,0.00009706148,0.0003558331,0.0006997577,0.00006296612,0.00534572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003074671,"threshold_uncertainty_score":0.01028579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233764095400079,"score_gpt":0.259437629310948,"score_spread":0.2470999883569472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}