{"id":"W2151232297","doi":"10.1200/jco.2000.18.7.1440","title":"Suramin Therapy for Patients With Symptomatic Hormone-Refractory Prostate Cancer: Results of a Randomized Phase III Trial Comparing Suramin Plus Hydrocortisone to Placebo Plus Hydrocortisone","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Medicine; Suramin; Placebo; Analgesic; Internal medicine; Hydrocortisone; Randomized controlled trial; Adverse effect; Anesthesia; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002125233,0.001298667,0.002506653,0.0003482176,0.0003038687,0.0009331778,0.0007544847,0.001374008,0.004349757],"category_scores_gemma":[0.002138034,0.0004870742,0.002018075,0.0003402841,0.0009696841,0.0007226181,0.000291769,0.001956786,0.0005177862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000590069,"about_ca_system_score_gemma":0.001050492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000883037,"about_ca_topic_score_gemma":0.001985891,"domain_scores_codex":[0.9990669,0.000631578,0.00006400042,0.0001093979,0.00005781564,0.00007041107],"domain_scores_gemma":[0.9984031,0.0005638296,0.0003975787,0.0000965822,0.00008467543,0.0004543656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9769098,0.004238443,0.0004244667,0.0005566056,0.001050175,0.00002479043,0.00003632993,0.0001814059,0.002693538,0.00003706898,0.0002934584,0.01355383],"study_design_scores_gemma":[0.9270818,0.07029783,0.00139378,0.00002686982,0.0004483612,0.00002507229,0.00001494421,0.0001931079,0.0002435817,0.00004236042,0.0002243105,0.00000801944],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841275,0.009821013,0.000686002,0.0007224726,0.0004812204,0.002389566,0.0006397286,0.0000726302,0.001059914],"genre_scores_gemma":[0.9878611,0.005080719,0.001495531,0.0009916474,0.0004781482,0.001940243,0.0009280435,0.00001589124,0.001208757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004349757,"threshold_uncertainty_score":0.0145514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04748725106251546,"score_gpt":0.4028778245394156,"score_spread":0.3553905734769002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}