{"id":"W2151232297","doi":"10.1200/jco.2000.18.7.1440","title":"Suramin Therapy for Patients With Symptomatic Hormone-Refractory Prostate Cancer: Results of a Randomized Phase III Trial Comparing Suramin Plus Hydrocortisone to Placebo Plus Hydrocortisone","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Medicine; Suramin; Placebo; Analgesic; Internal medicine; Hydrocortisone; Randomized controlled trial; Adverse effect; Anesthesia; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005073543,0.0004007504,0.006427007,0.0003092166,0.00009368253,0.00002318918,0.0003069239,0.0003831038,0.00008006518],"category_scores_gemma":[0.00357976,0.0002670135,0.00105822,0.0003025284,0.0004947444,0.0002018122,0.00002768703,0.0007785081,0.000005189604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005095634,"about_ca_system_score_gemma":0.003660562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004083985,"about_ca_topic_score_gemma":0.0001077728,"domain_scores_codex":[0.990662,0.001202386,0.006333418,0.0004208773,0.0008269668,0.0005543171],"domain_scores_gemma":[0.9859212,0.007623968,0.004728218,0.0004115789,0.0007378484,0.0005771826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7914778,0.004630958,0.0007017992,0.00005888243,0.001076289,0.00009431515,0.0009503553,0.0004231548,0.0001142563,0.00000107121,0.001475566,0.1989955],"study_design_scores_gemma":[0.8905255,0.07695641,0.007082858,0.0005910484,0.0009016542,0.00008418526,0.000102345,0.003277161,0.00008259308,0.00001173314,0.02011807,0.0002664363],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885366,0.002601036,0.0001247265,0.001261892,0.000716014,0.006481795,0.00004269421,0.00002403474,0.0002112124],"genre_scores_gemma":[0.9868059,0.009488067,0.0006929247,0.0004299158,0.00123773,0.0003390555,0.00003369139,0.00006025084,0.0009124761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1987291,"threshold_uncertainty_score":0.9999782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04748725106251546,"score_gpt":0.4028778245394156,"score_spread":0.3553905734769002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}