{"id":"W2151260513","doi":"10.1093/carcin/bgr289","title":"A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis","year":2011,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Calgary","funders":"Canadian Institutes of Health Research; Canada Research Chairs; University of Calgary","keywords":"Microglia; Glioma; Chemokine; CCR2; CCL2; Cancer research; Biology; Cell culture; CD68; Immunology; Immune system; Inflammation; Immunohistochemistry; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002206831,0.0002912615,0.000515976,0.00007902212,0.0001898477,0.0000373937,0.0002117638,0.0001073769,0.0002530245],"category_scores_gemma":[0.00008628942,0.0001912069,0.0001948068,0.0002445618,0.000237559,0.000100153,0.000158205,0.0001606583,0.00002344537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006005341,"about_ca_system_score_gemma":0.0000943462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006777919,"about_ca_topic_score_gemma":0.00003305337,"domain_scores_codex":[0.9985458,0.00007943219,0.0002926805,0.0004427502,0.0002463173,0.0003929914],"domain_scores_gemma":[0.9989822,0.0001578973,0.0001203231,0.000462369,0.0001180698,0.0001591446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001353272,0.00009244557,0.7969624,0.0002725706,0.0002448194,0.0001959773,0.005999441,7.07467e-8,0.1896418,0.00006531268,0.000449481,0.005940401],"study_design_scores_gemma":[0.0007973262,0.0001742992,0.1830831,0.000145234,0.0003680496,0.0002699261,0.0005687058,0.000004009002,0.812774,0.0003702368,0.001223376,0.0002217049],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944444,0.002898412,0.0001341128,0.0004067949,0.0001638422,0.0005362525,0.00002922546,0.00006754296,0.00131939],"genre_scores_gemma":[0.9984017,0.00006723798,0.0005098057,0.0003153016,0.0004299803,0.00005392644,0.00002038974,0.00005517851,0.0001465071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6231322,"threshold_uncertainty_score":0.7797191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07592301793658124,"score_gpt":0.2608484461027734,"score_spread":0.1849254281661921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}