{"id":"W2151289840","doi":"10.1093/eurheartj/ehr383","title":"Cardiac phenotype and clinical outcome of familial amyloid polyneuropathy associated with transthyretin alanine 60 variant","year":2011,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":195,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"King's College London; Medical Research Council; National Institute for Health and Care Research","keywords":"Medicine; Transthyretin; Cardiac amyloidosis; Amyloidosis; Liver transplantation; Internal medicine; Polyneuropathy; Gastroenterology; Transplantation; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001066027,0.0002596657,0.0004588317,0.00005863083,0.0001178576,0.00002618481,0.000195402,0.00009193086,0.0000542359],"category_scores_gemma":[0.0002915784,0.0001993327,0.0002637942,0.00008655956,0.000205959,0.000009692191,0.00008610181,0.000323552,0.00001940803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001446343,"about_ca_system_score_gemma":0.00005904152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001731913,"about_ca_topic_score_gemma":0.00001081882,"domain_scores_codex":[0.9975266,0.0009385219,0.0006197818,0.0003615957,0.0002202126,0.0003332246],"domain_scores_gemma":[0.9989555,0.00006490835,0.0002973404,0.0003049614,0.000116124,0.0002611032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003292683,0.000336136,0.985677,0.000006143762,0.000405814,0.0002648378,0.0001831496,0.000001883572,0.01103227,0.00001270658,0.0009282387,0.0008225545],"study_design_scores_gemma":[0.001747989,0.002085617,0.9889546,0.00003525786,0.0002142819,0.0001720449,0.00006268979,0.000003136033,0.0034739,0.00000324951,0.003015917,0.0002313429],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959343,0.0006115153,0.000145078,0.0001554795,0.0003456007,0.0001553872,0.0000492291,0.00001874854,0.00258465],"genre_scores_gemma":[0.9972264,0.0006457164,0.001014884,0.0004299207,0.0003388798,0.000001793384,0.00002111208,0.00007223409,0.0002490928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007558369,"threshold_uncertainty_score":0.8128551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04316174043089756,"score_gpt":0.2902855079690659,"score_spread":0.2471237675381684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}