{"id":"W2151347057","doi":"10.1182/blood-2002-02-0632","title":"All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":498,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Acute promyelocytic leukemia; Medicine; Cytarabine; Internal medicine; White blood cell; Gastroenterology; Tretinoin; Retinoic acid; Regimen; Maintenance therapy; Daunorubicin; Chemotherapy; Cumulative incidence; Randomized controlled trial; Oncology; Immunology; Transplantation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008215501,0.0002927344,0.0003527539,0.00006883445,0.0000739398,0.00007779473,0.0004198678,0.0001229013,0.0000451742],"category_scores_gemma":[0.00008627897,0.0002098733,0.000153259,0.0004564413,0.0002344236,0.000009108223,0.0001337468,0.0002667136,0.000006727388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003530915,"about_ca_system_score_gemma":0.00004923415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007229509,"about_ca_topic_score_gemma":0.0008915841,"domain_scores_codex":[0.9983098,0.0001156623,0.0004112706,0.0006020924,0.0001914459,0.0003697659],"domain_scores_gemma":[0.9991224,0.00003724751,0.000177014,0.0005141177,0.00004795591,0.0001012003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004233173,0.0001566654,0.9682823,0.00005047155,0.0007695351,0.00005082439,0.0002168179,0.000004660341,0.02908941,5.203186e-7,0.00002288212,0.00131355],"study_design_scores_gemma":[0.001858074,0.0004017109,0.9407099,0.00002519869,0.00103984,0.00002372739,0.00003872545,0.0001079006,0.05508209,0.000003490512,0.0003370515,0.000372221],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918008,0.0002250903,0.0003569366,0.0001092652,0.00001977054,0.007343381,0.00004706991,0.00002351976,0.00007409752],"genre_scores_gemma":[0.991142,0.000115017,0.0002370699,0.0002074697,0.0001105992,0.007906632,0.0001370327,0.00003048407,0.0001137078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02757236,"threshold_uncertainty_score":0.8558383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396033276629682,"score_gpt":0.2607257576009052,"score_spread":0.2467654248346083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}