{"id":"W2151347057","doi":"10.1182/blood-2002-02-0632","title":"All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":498,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Acute promyelocytic leukemia; Medicine; Cytarabine; Internal medicine; White blood cell; Gastroenterology; Tretinoin; Retinoic acid; Regimen; Maintenance therapy; Daunorubicin; Chemotherapy; Cumulative incidence; Randomized controlled trial; Oncology; Immunology; Transplantation; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01444345,0.001615335,0.00259989,0.001373656,0.002325712,0.001921272,0.002524119,0.001989011,0.01309126],"category_scores_gemma":[0.0072987,0.0006465144,0.002438613,0.002552205,0.001001702,0.001177085,0.001843279,0.00197579,0.004687305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003603319,"about_ca_system_score_gemma":0.0105564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002448971,"about_ca_topic_score_gemma":0.004750677,"domain_scores_codex":[0.9924142,0.004725306,0.001050351,0.0004994075,0.0006989157,0.0006118924],"domain_scores_gemma":[0.995239,0.0006276285,0.001114671,0.001011177,0.001326973,0.0006805028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6230106,0.02161572,0.04847968,0.01686355,0.003827747,0.001376389,0.001401641,0.008006811,0.01369289,0.008451742,0.07676444,0.1765088],"study_design_scores_gemma":[0.3489978,0.0961696,0.2147494,0.006862166,0.004386912,0.001530264,0.0009546575,0.006752307,0.007475818,0.007019295,0.3047364,0.0003652841],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"empirical","genre_scores_codex":[0.07109234,0.003299956,0.008860258,0.0008969762,0.0003324134,0.8705222,0.02469894,0.0001642701,0.02013272],"genre_scores_gemma":[0.05275889,0.001780938,0.007549463,0.0007935084,0.0001480538,0.9171803,0.01617505,0.00004814885,0.003565611],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01444345,"threshold_uncertainty_score":0.0763852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396033276629682,"score_gpt":0.2607257576009052,"score_spread":0.2467654248346083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}