{"id":"W2151435349","doi":"10.1042/bse0420013","title":"Control of gene expression and mitochondrial biogenesis in the muscular adaptation to endurance exercise","year":2006,"lang":"en","type":"review","venue":"Essays in Biochemistry","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Lundbeckfonden","keywords":"Mitochondrial biogenesis; TFAM; Coactivator; Mitochondrial DNA; mitochondrial fusion; Biology; Mitochondrion; PPARGC1A; Endurance training; Gene; Biogenesis; Gene expression; Cell biology; Transcription factor; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003842005,0.0007935544,0.001304202,0.001384019,0.0003217082,0.0007821193,0.0006410286,0.001010032,0.001433303],"category_scores_gemma":[0.0003195254,0.000233651,0.0002733209,0.001697869,0.0008904393,0.001269167,0.0005644538,0.001068237,0.002118345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006331242,"about_ca_system_score_gemma":0.0005011965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006048547,"about_ca_topic_score_gemma":0.0009850679,"domain_scores_codex":[0.9998264,0.00002757557,0.00002124062,0.00003602338,0.00007528968,0.00001353457],"domain_scores_gemma":[0.9998902,0.00004308971,0.00001754642,0.000005291991,0.0000304626,0.00001334837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001157522,0.00008741842,0.0002832041,0.006868511,0.00005415307,0.0005448765,0.0001795976,0.0005689145,0.01235142,0.00765396,0.0178421,0.9534501],"study_design_scores_gemma":[0.00001827464,0.0001000329,0.001778674,0.001147445,0.00003769527,0.00240858,0.0001468328,0.0001211279,0.002457197,0.004731061,0.987031,0.00002204288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002561758,0.9974884,0.0003063124,0.0002092206,0.0003122338,0.000003371438,0.000005482048,0.00000915966,0.001409681],"genre_scores_gemma":[0.001547625,0.9962267,0.0003270223,0.0001292097,0.0002451055,0.000006142852,0.00001156789,0.000002009519,0.00150458],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001433303,"threshold_uncertainty_score":0.004794896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02106746619696574,"score_gpt":0.2942697726284856,"score_spread":0.2732023064315199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}