{"id":"W2151442356","doi":"10.1042/bj20071372","title":"A Ca2+-dependent bacterial antifreeze protein domain has a novel β-helical ice-binding fold","year":2008,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":144,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Environment Research Council; Sight Research UK","keywords":"Antifreeze protein; Antifreeze; Chemistry; Biochemistry; Asparagine; Amino acid; Freezing point; Aspartic acid; Homology modeling; Protein structure; Biophysics; Crystallography; Stereochemistry; Biology; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001956343,0.0002554198,0.0002712916,0.00003188322,0.0005068315,0.00008713299,0.0005030146,0.0002252734,0.002446434],"category_scores_gemma":[0.0001548069,0.0001837113,0.0002193269,0.0002407895,0.0006054388,0.0001744237,0.0003596788,0.0005734228,0.0005615246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002143474,"about_ca_system_score_gemma":0.00004654909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004290994,"about_ca_topic_score_gemma":0.000003105972,"domain_scores_codex":[0.9978328,0.00005210819,0.0004633416,0.0004448851,0.000624049,0.000582761],"domain_scores_gemma":[0.9990525,0.00005065123,0.0001585555,0.0001967105,0.00002176826,0.0005198309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001228175,0.0004299716,0.0003778997,0.000003042197,0.00001649224,0.00005784207,0.00005700452,0.000003370313,0.9923248,0.00003444508,0.00633976,0.0002325511],"study_design_scores_gemma":[0.001543585,0.0002053275,0.007260158,0.00004765658,0.00001732408,0.001171991,0.00003519156,0.0000578262,0.9773626,0.001716323,0.01008527,0.0004966899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965191,0.00002997946,0.001027817,0.001105765,0.0001415977,0.0002072566,0.00003499411,0.00005255136,0.000880873],"genre_scores_gemma":[0.9900732,0.00001300549,0.008644906,0.0002330378,0.0006010752,0.0000210236,0.00002212275,0.0000162119,0.0003754369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01496215,"threshold_uncertainty_score":0.9984655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04004948795958202,"score_gpt":0.224929625698237,"score_spread":0.1848801377386549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}