{"id":"W2151624523","doi":"10.1093/molbev/mss076","title":"Comparative Genomics Reveals Adaptive Protein Evolution and a Possible Cytonuclear Incompatibility between European and American Eels","year":2012,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada","keywords":"Biology; Reproductive isolation; Nonsynonymous substitution; Nuclear gene; Genetics; Gene; Negative selection; Epistasis; Gene flow; Evolutionary biology; Comparative genomics; Concerted evolution; Phylogenetics; Genome; Genomics; Genetic variation; Population","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001249217,0.0001289427,0.000154451,0.0003810317,0.0001640509,0.0003160775,0.0001109104,0.0002182544,0.0003210185],"category_scores_gemma":[0.000168551,0.00008024074,0.0002033723,0.0003339881,0.0001881112,0.0001280095,0.000219345,0.0001879682,0.00008198278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001246302,"about_ca_system_score_gemma":0.00007979695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006261652,"about_ca_topic_score_gemma":0.001124203,"domain_scores_codex":[0.9999242,0.000008397785,0.000004657683,0.00003268845,0.00001302279,0.00001705683],"domain_scores_gemma":[0.9998797,0.00003143627,0.00003777472,0.00001125136,0.00001092203,0.00002880826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000198217,0.00002913117,0.0273328,0.00002344133,0.00004647818,0.0001387676,0.0002395864,0.00007912407,0.9686112,0.0001620943,0.00002245636,0.003116589],"study_design_scores_gemma":[0.000007498124,0.0001197722,0.9783229,0.000003970309,0.00004654206,0.000455463,0.000268549,0.0008903122,0.01871605,0.000112374,0.001049482,0.000006993347],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999598,0.00007541705,0.0001264573,0.000006912455,5.288675e-7,6.883644e-7,0.00007421611,0.000002759052,0.0001151454],"genre_scores_gemma":[0.9988883,0.00006553961,0.0003039633,0.00002381617,0.000002170219,0.000003885174,0.0004794507,0.000003688705,0.0002292799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006261652,"threshold_uncertainty_score":0.001245022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01966929558260709,"score_gpt":0.2860532200903058,"score_spread":0.2663839245076987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}