{"id":"W2151638388","doi":"10.1200/jco.2006.09.4490","title":"Immunohistochemical Prognostic Markers in Diffuse Large B-Cell Lymphoma: Validation of Tissue Microarray As a Prerequisite for Broad Clinical Applications—A Study From the Lunenburg Lymphoma Biomarker Consortium","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":305,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Takeda Oncology; Genentech","keywords":"Tissue microarray; Immunohistochemistry; Medicine; Concordance; Lymphoma; Biomarker; Pathology; Diffuse large B-cell lymphoma; Oncology; CD20; Follicular lymphoma; Internal medicine; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01742386,0.0003979467,0.0004405889,0.0007998942,0.0005449114,0.0009585173,0.0009041797,0.0006485513,0.0005076697],"category_scores_gemma":[0.01264395,0.0002938316,0.00030077,0.000858699,0.0008250676,0.0004403036,0.0007470068,0.0005406219,0.0002995147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007798155,"about_ca_system_score_gemma":0.0006908249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001887813,"about_ca_topic_score_gemma":0.001348976,"domain_scores_codex":[0.9888893,0.005502688,0.0006975826,0.001808135,0.002837003,0.0002652792],"domain_scores_gemma":[0.990535,0.003698345,0.0012616,0.001913983,0.002180765,0.0004104216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003657922,0.001062938,0.8687706,0.0002544083,0.000469317,0.0003416471,0.00107582,0.001624339,0.05604385,0.0002070206,0.0007778563,0.06571431],"study_design_scores_gemma":[0.0003643694,0.003565686,0.9566782,0.00006080906,0.0004205981,0.001723566,0.0003537507,0.004743068,0.02829582,0.0001655164,0.003586323,0.00004225441],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939594,0.001260022,0.003740054,0.0001046465,0.00001529357,0.0001621886,0.0001699126,0.00002728062,0.0005611528],"genre_scores_gemma":[0.9949397,0.0001930688,0.003662385,0.0001112374,0.00002966274,0.0001393595,0.0007060855,0.00001571532,0.0002027618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01742386,"threshold_uncertainty_score":0.09214723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05768192276787162,"score_gpt":0.4388685669305694,"score_spread":0.3811866441626978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}