{"id":"W2151682201","doi":"10.1371/journal.pone.0137568","title":"Detection of Hepatitis B Virus (HBV) Genomes and HBV Drug Resistant Variants by Deep Sequencing Analysis of HBV Genomes in Immune Cell Subsets of HBV Mono-Infected and/or Human Immunodeficiency Virus Type-1 (HIV-1) and HBV Co-Infected Individuals","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Janssen Pharmaceuticals; China Scholarship Council; Canadian Liver Foundation; Canadian Institutes of Health Research; Bristol-Myers Squibb","keywords":"Virology; Hepatitis B virus; Biology; Hepatitis B; HBsAg; Orthohepadnavirus; cccDNA; Hepadnaviridae; Population; Virus; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001572111,0.0001218207,0.0001529352,0.0003270794,0.0001619777,0.0002554503,0.0001027609,0.0001716774,0.0008743219],"category_scores_gemma":[0.000275097,0.0001193601,0.0001115554,0.0001230794,0.0001252106,0.000101636,0.0002204325,0.0001439823,0.0001517467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006791834,"about_ca_system_score_gemma":0.0000620486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003476314,"about_ca_topic_score_gemma":0.0006265828,"domain_scores_codex":[0.9999138,0.00001767792,0.00000869512,0.00002630938,0.00001650406,0.00001708945],"domain_scores_gemma":[0.9998928,0.00002620756,0.00002401262,0.00001171947,0.00002469999,0.00002054512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007595957,0.00005400948,0.1557024,0.00009659668,0.00004101422,0.0001416833,0.0003484458,0.0002076579,0.8285267,0.00005835526,0.00008472674,0.0139788],"study_design_scores_gemma":[0.00003756848,0.001388935,0.7531377,0.00004855189,0.0001639972,0.004022087,0.001055705,0.007169239,0.2302136,0.0002949413,0.00245183,0.00001583283],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983947,0.0002060639,0.0009310996,0.0000113906,0.000002061419,0.00000938162,0.00016585,0.000008575224,0.0002709149],"genre_scores_gemma":[0.996186,0.0001538163,0.002707243,0.00004011656,0.000004471336,0.00002311121,0.0004739438,0.000005099413,0.0004061913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008743219,"threshold_uncertainty_score":0.00292486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03652827534121846,"score_gpt":0.2593916249853923,"score_spread":0.2228633496441738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}