{"id":"W2151682201","doi":"10.1371/journal.pone.0137568","title":"Detection of Hepatitis B Virus (HBV) Genomes and HBV Drug Resistant Variants by Deep Sequencing Analysis of HBV Genomes in Immune Cell Subsets of HBV Mono-Infected and/or Human Immunodeficiency Virus Type-1 (HIV-1) and HBV Co-Infected Individuals","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Janssen Pharmaceuticals; China Scholarship Council; Canadian Liver Foundation; Canadian Institutes of Health Research; Bristol-Myers Squibb","keywords":"Virology; Hepatitis B virus; Biology; Hepatitis B; HBsAg; Orthohepadnavirus; cccDNA; Hepadnaviridae; Population; Virus; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009708417,0.0004469319,0.001975143,0.001228274,0.000177461,0.00003320256,0.0001630097,0.0002240066,0.00007310457],"category_scores_gemma":[0.0005993121,0.0004218357,0.000106729,0.001748466,0.000438648,0.0002398362,0.0002208871,0.0003187291,0.000004190075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003005564,"about_ca_system_score_gemma":0.0001879374,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.0324147,"about_ca_topic_score_gemma":0.02468562,"domain_scores_codex":[0.9963349,0.0003560227,0.001455109,0.0006164066,0.0007307599,0.0005068453],"domain_scores_gemma":[0.997395,0.0003343222,0.0008656101,0.0005742468,0.0006372877,0.0001935771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002569796,0.0006716031,0.4224828,0.0004060238,0.001186013,0.00001647201,0.004136904,0.000006312385,0.5705273,0.000004927917,0.000008089098,0.0002966339],"study_design_scores_gemma":[0.002370795,0.0009274913,0.6267179,0.0003257759,0.002593581,0.00000526571,0.0003883048,0.001160803,0.3651177,0.00003670034,0.0000133256,0.0003423917],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777831,0.02035904,0.00003740975,0.00002652298,0.00002905993,0.0008551156,0.0005870818,0.00006214486,0.0002605378],"genre_scores_gemma":[0.9882111,0.01071994,0.0006452902,0.00002331341,0.00001843634,0.00004385417,0.0001765715,0.00005945317,0.0001020681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2054096,"threshold_uncertainty_score":0.9998233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03652827534121846,"score_gpt":0.2593916249853923,"score_spread":0.2228633496441738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}