{"id":"W2151686792","doi":"10.1053/j.gastro.2012.09.057","title":"Mice That Express Human Interleukin-8 Have Increased Mobilization of Immature Myeloid Cells, Which Exacerbates Inflammation and Accelerates Colon Carcinogenesis","year":2012,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":209,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Alberta Heritage Foundation for Medical Research","keywords":"Inflammation; Carcinogenesis; Immune system; CXC chemokine receptors; Cancer research; Immunology; Biology; Myeloid; Interleukin; Colorectal cancer; Cancer; Chemokine; Chemokine receptor; Cytokine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002558481,0.001012143,0.0005361772,0.001164509,0.0002051575,0.0004274851,0.0002525905,0.0007907825,0.003698981],"category_scores_gemma":[0.0002177075,0.000460546,0.0004443615,0.0003049224,0.0005902082,0.0004291532,0.0003232041,0.001921381,0.0008569309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002836034,"about_ca_system_score_gemma":0.000241044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001671734,"about_ca_topic_score_gemma":0.0003539271,"domain_scores_codex":[0.9996504,0.00006434879,0.00003460918,0.00006790315,0.00009040238,0.00009240272],"domain_scores_gemma":[0.9993883,0.00005274085,0.0002717722,0.00006574092,0.00002672333,0.0001947443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006035782,0.0001153976,0.0004621091,0.00002751917,0.000007663714,0.0001340246,0.00001425687,0.00005710186,0.9973713,0.0001433404,0.00007654165,0.0009871362],"study_design_scores_gemma":[0.0006293669,0.002968318,0.02044177,0.00003268688,0.0001186164,0.002969009,0.0001426094,0.001564086,0.9661556,0.0005491562,0.004391882,0.00003689767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960735,0.0005252555,0.001598312,0.0002828989,0.00004513463,0.00002773743,0.0004918238,0.0002161606,0.0007392699],"genre_scores_gemma":[0.9889433,0.0007070021,0.003398069,0.0001638379,0.00004033987,0.00009394126,0.0008082453,0.00009520382,0.005749995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003698981,"threshold_uncertainty_score":0.01237428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01682528875475777,"score_gpt":0.2499106458321673,"score_spread":0.2330853570774095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}