{"id":"W2151686920","doi":"10.1016/j.fertnstert.2011.01.012","title":"In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates","year":2011,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Oregon National Primate Research Center; U.S. Public Health Service; National Institutes of Health; Canadian Institutes of Health Research; National Center for Research Resources; Battelle","keywords":"Ovarian reserve; Ovarian cancer; Fertility preservation; Physiology; Ovary; Medicine; Fertility; Reproductive medicine; Offspring; Premature ovarian failure; Andrology; Infertility; Oncology; Biology; Internal medicine; Cancer; Pregnancy; Population","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004872311,0.0001531559,0.0002776025,0.00005461777,0.00004205809,0.00001225984,0.0001052403,0.0001753522,0.00004555527],"category_scores_gemma":[0.0001318155,0.0001516336,0.00004294224,0.00008392223,0.00009732958,0.00002955871,0.0001293774,0.00009968405,3.177429e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001107686,"about_ca_system_score_gemma":0.00004480004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001540735,"about_ca_topic_score_gemma":0.001774735,"domain_scores_codex":[0.9987159,0.0001641311,0.000414467,0.0004126775,0.00008731076,0.0002055623],"domain_scores_gemma":[0.9994515,0.00001645139,0.00008380975,0.0003127985,0.00005931421,0.00007609741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003368688,0.0002611156,0.7189332,0.0002370095,0.00001790817,0.000001942657,0.001830558,7.646134e-7,0.2741429,0.00001417234,0.00000378495,0.001187999],"study_design_scores_gemma":[0.0007941116,0.00007015458,0.8120318,0.00002017138,0.00000809019,8.99777e-7,0.0001401107,0.00006331238,0.1865133,0.0002125509,0.00003848983,0.0001070448],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990935,0.0003220155,0.00003625382,0.00001723411,0.00006023205,0.0002654595,0.0000382596,0.00000548336,0.0001615143],"genre_scores_gemma":[0.9995525,0.00004896221,0.000256423,0.00007117627,0.00002005713,0.00001732493,0.00001440381,0.000006772957,0.0000123289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09309862,"threshold_uncertainty_score":0.6183439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01701629073393218,"score_gpt":0.237776073937042,"score_spread":0.2207597832031098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}