{"id":"W2151849899","doi":"10.1158/1940-6207.capr-08-0206","title":"Five-Year Efficacy and Safety Analysis of the Adenoma Prevention with Celecoxib Trial","year":2009,"lang":"en","type":"article","venue":"Cancer Prevention Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Claude Pepper Older Americans Independence Center, Wake Forest School of Medicine; University of Illinois at Urbana-Champaign; Dartmouth College; University of Minnesota; Memorial Sloan-Kettering Cancer Center; Massachusetts General Hospital; McMaster University; Vanderbilt University; National Cancer Institute; Brigham and Women's Hospital; Johns Hopkins University; Vanderbilt University Medical Center; Wake Forest University; Pfizer; U.S. Department of Veterans Affairs","keywords":"Celecoxib; Medicine; Placebo; Adverse effect; Adenoma; Internal medicine; Colorectal adenoma; Colorectal cancer; Colonoscopy; Incidence (geometry); Clinical trial; Gastroenterology; Surgery; Cancer; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003980356,0.0007504691,0.001604462,0.0004717665,0.0003920108,0.001108091,0.0005189854,0.001310645,0.004934283],"category_scores_gemma":[0.004553135,0.0003033144,0.0027341,0.0005846947,0.000409894,0.000674581,0.0004254013,0.002075736,0.0005503942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005362838,"about_ca_system_score_gemma":0.0006781035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007314616,"about_ca_topic_score_gemma":0.00134698,"domain_scores_codex":[0.9980149,0.00127086,0.0001221464,0.0001890667,0.0002290093,0.0001739575],"domain_scores_gemma":[0.9975182,0.0006408582,0.0008022437,0.0002127314,0.0002851932,0.0005409601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9440883,0.002318242,0.01691399,0.001261611,0.006743009,0.0001794649,0.00006241535,0.000787641,0.001701021,0.000489398,0.003821676,0.02163335],"study_design_scores_gemma":[0.7358203,0.08551621,0.1508432,0.0003386697,0.01364287,0.0004438048,0.00009367531,0.00254212,0.001275213,0.001336285,0.008045242,0.0001024459],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9558647,0.02371159,0.001211963,0.001360818,0.0004444676,0.001509168,0.005887484,0.000119114,0.009890647],"genre_scores_gemma":[0.9858069,0.003343047,0.0004860905,0.001050236,0.0004093896,0.0007400531,0.006156103,0.00001449308,0.001993591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004934283,"threshold_uncertainty_score":0.02105039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03977779682572644,"score_gpt":0.4003608574561844,"score_spread":0.360583060630458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}