{"id":"W2151849899","doi":"10.1158/1940-6207.capr-08-0206","title":"Five-Year Efficacy and Safety Analysis of the Adenoma Prevention with Celecoxib Trial","year":2009,"lang":"en","type":"article","venue":"Cancer Prevention Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Claude Pepper Older Americans Independence Center, Wake Forest School of Medicine; University of Illinois at Urbana-Champaign; Dartmouth College; University of Minnesota; Memorial Sloan-Kettering Cancer Center; Massachusetts General Hospital; McMaster University; Vanderbilt University; National Cancer Institute; Brigham and Women's Hospital; Johns Hopkins University; Vanderbilt University Medical Center; Wake Forest University; Pfizer; U.S. Department of Veterans Affairs","keywords":"Celecoxib; Medicine; Placebo; Adverse effect; Adenoma; Internal medicine; Colorectal adenoma; Colorectal cancer; Colonoscopy; Incidence (geometry); Clinical trial; Gastroenterology; Surgery; Cancer; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001340782,0.00009447813,0.0003139155,0.0003005296,0.0001461242,0.00001560198,0.0001043933,0.0000847588,0.0003976796],"category_scores_gemma":[0.0001479826,0.00006011606,0.0001524315,0.001259483,0.0001337008,0.00006284573,0.00003451591,0.0002997946,0.000003432656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001082332,"about_ca_system_score_gemma":0.0003242825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003680484,"about_ca_topic_score_gemma":0.0000878877,"domain_scores_codex":[0.9981522,0.0004290866,0.0002667017,0.0002511269,0.0006538235,0.000247059],"domain_scores_gemma":[0.9990793,0.0001169696,0.0001091178,0.0003354952,0.0002506889,0.0001083773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.3316069,0.004353056,0.1592219,0.001416115,0.007828389,0.00006943031,0.004122391,0.0007889527,0.03238271,0.004846663,0.009252735,0.4441108],"study_design_scores_gemma":[0.03939733,0.003359935,0.9480905,0.0004641225,0.001150528,0.000003057461,0.0001109377,0.0003954398,0.004801755,0.0002074185,0.001901767,0.0001172239],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962926,0.0004484938,0.00008890581,0.0005686624,0.000074949,0.001616556,0.000006736853,0.00001359914,0.0008895054],"genre_scores_gemma":[0.9946905,0.0002174439,0.00006112323,0.00002428067,0.0001797955,0.00006813656,0.00001604724,0.000008873477,0.004733818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7888686,"threshold_uncertainty_score":0.4354313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03977779682572644,"score_gpt":0.4003608574561844,"score_spread":0.360583060630458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}