{"id":"W2151877201","doi":"10.1128/aac.00509-11","title":"Enhanced Neutralization of HIV by Antibodies Displayed on the S-Layer of Caulobacter crescentus","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Caulobacter crescentus; Antibody; Neutralization; S-layer; Epitope; Human immunodeficiency virus (HIV); Virology; Biology; Microbiology; Chemistry; Bacteria; Immunology; Bacterial protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001190993,0.0003798617,0.0001303398,0.0001521293,0.000115844,0.0002543106,0.0001801513,0.0001885298,0.0003655085],"category_scores_gemma":[0.0001112731,0.00008306505,0.0001746224,0.0001396682,0.0001596896,0.0001321443,0.0001850695,0.0002749151,0.0001452883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002807618,"about_ca_system_score_gemma":0.0002623239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005474579,"about_ca_topic_score_gemma":0.004659336,"domain_scores_codex":[0.9999188,0.00001153745,0.000005476299,0.00001441681,0.00002651998,0.00002326137],"domain_scores_gemma":[0.9999385,0.000008161021,0.00001631007,0.000006898139,0.00001494306,0.00001523903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002141219,0.000009810866,0.0001029162,0.00001932955,0.000002163456,0.00003115307,0.000007083409,0.00004508554,0.9991731,0.00002575672,0.00001865447,0.000543564],"study_design_scores_gemma":[0.00001304252,0.0002604969,0.00347229,0.000009747439,0.00001261842,0.0001766637,0.00003374916,0.0007537907,0.9934883,0.00001993783,0.001754021,0.000005226213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997453,0.0004901502,0.0009282934,0.00007515481,0.00001652555,0.00001844179,0.0001215099,0.00002608523,0.0008707696],"genre_scores_gemma":[0.9933348,0.0004893717,0.003651685,0.00009037465,0.00000613772,0.00001196497,0.0003792887,0.00001699937,0.002019495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005474579,"threshold_uncertainty_score":0.01088542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03659696013545519,"score_gpt":0.2850632674353739,"score_spread":0.2484663072999187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}