{"id":"W2151879455","doi":"10.1152/ajpcell.00126.2002","title":"PAR<sub>1</sub>-dependent and independent increases in COX-2 and PGE<sub>2</sub> in human colonic myofibroblasts stimulated by thrombin","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Thrombin; Chemistry; Prostaglandin E; Cyclooxygenase; Prostaglandin; Secretion; Endocrinology; Prostaglandin E2; Internal medicine; Molecular biology; Biochemistry; Platelet; Enzyme; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000194652,0.0003168402,0.0003365403,0.0002575719,0.0001384092,0.0002900422,0.0000947102,0.0003158654,0.001881562],"category_scores_gemma":[0.0001788967,0.0001954601,0.0004238563,0.0001724227,0.0001964934,0.0002382919,0.0001649404,0.0004778154,0.0006407299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001800656,"about_ca_system_score_gemma":0.0001154136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003932099,"about_ca_topic_score_gemma":0.0006208802,"domain_scores_codex":[0.9997949,0.00004032822,0.00002485595,0.00003497888,0.00004305644,0.00006187386],"domain_scores_gemma":[0.9998498,0.00002466762,0.00003732198,0.00001931543,0.00002332298,0.00004552264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004353017,0.00002180035,0.0003474264,0.00004477955,0.000004545343,0.0001902413,0.00001805007,0.00001080111,0.9985284,0.00002185226,0.0000273934,0.0003495218],"study_design_scores_gemma":[0.00009570165,0.0009137944,0.07650583,0.00001223688,0.00005816207,0.001879531,0.0001380003,0.0007282681,0.9175959,0.00005245478,0.002011005,0.00000901801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940369,0.002891026,0.001410658,0.00009264,0.00003976133,0.00005899107,0.0006142493,0.00002623151,0.000829466],"genre_scores_gemma":[0.9921514,0.001800685,0.0021948,0.000127763,0.00006871021,0.0001726072,0.001116121,0.0000141534,0.002353749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001881562,"threshold_uncertainty_score":0.006294489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008160028641605291,"score_gpt":0.2434889406700888,"score_spread":0.2353289120284835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}