{"id":"W2151906803","doi":"10.1139/o07-154","title":"A comparison of Hsp90α and Hsp90β interactions with cochaperones and substrates","year":2008,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hsp90; Xenopus; Heat shock protein; Chaperone (clinical); Gene isoform; Biology; CDC37; Immunoprecipitation; Cell biology; Co-chaperone; HSF1; Hsp70; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006042204,0.0001322727,0.0001875298,0.00002337637,0.0001061897,0.00000679325,0.0000643499,0.0001605987,0.00001510793],"category_scores_gemma":[0.00002667495,0.0001088619,0.00001708541,0.00004252683,0.0006196121,0.000002963294,0.0001011052,0.0001082864,6.074241e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003309911,"about_ca_system_score_gemma":0.00005329376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003025982,"about_ca_topic_score_gemma":0.00001321016,"domain_scores_codex":[0.9992683,0.00003458677,0.0001553397,0.0003202165,0.00004351273,0.0001780495],"domain_scores_gemma":[0.9995985,0.00002779903,0.00005319049,0.0001599826,0.00005813755,0.0001024128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001343078,0.00006155173,0.05861581,0.00007869093,0.0000247342,0.000002333779,0.00006836412,4.808477e-7,0.9400537,0.00001364844,0.000073135,0.000873217],"study_design_scores_gemma":[0.0004299989,0.0004884087,0.00286421,0.00001245403,0.000009094207,0.0001232389,0.0002497343,0.00003028719,0.9920526,0.000009788735,0.003601026,0.0001292191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930929,0.005253551,0.00006822141,0.00007897802,0.00001151503,0.00009951839,0.00002034257,0.000005825076,0.001369178],"genre_scores_gemma":[0.9978313,0.001099854,0.0004064937,0.00001965794,0.00004632461,0.00001644735,0.0000673641,0.000008808874,0.0005037096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0557516,"threshold_uncertainty_score":0.4439259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02304194459419756,"score_gpt":0.3080794715065667,"score_spread":0.2850375269123691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}