{"id":"W2151918137","doi":"10.1158/0008-5472.can-06-0018","title":"IMC-EB10, an Anti-FLT3 Monoclonal Antibody, Prolongs Survival and Reduces Nonobese Diabetic/Severe Combined Immunodeficient Engraftment of Some Acute Lymphoblastic Leukemia Cell Lines and Primary Leukemic Samples","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Center for Research Resources; Wellcome Trust; Leukemia and Lymphoma Society","keywords":"Monoclonal antibody; Cancer research; Nod; Leukemia; Antibody; In vivo; Cell sorting; Cell culture; Acute lymphocytic leukemia; Immunotherapy; Medicine; Immunology; Biology; Immune system; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001577052,0.0005025745,0.000485532,0.000260742,0.0001097895,0.0002231309,0.0002901761,0.0002483324,0.001061735],"category_scores_gemma":[0.00008181253,0.0001290267,0.0002111652,0.0001647918,0.0001481513,0.0001216916,0.0001241039,0.0009650362,0.0002622258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000308014,"about_ca_system_score_gemma":0.0002600927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001219859,"about_ca_topic_score_gemma":0.002988575,"domain_scores_codex":[0.9998511,0.00002086902,0.00001356888,0.0000238707,0.00003747746,0.00005312346],"domain_scores_gemma":[0.9998989,0.00001345469,0.0000203717,0.00001187706,0.00001015257,0.0000452916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004281048,0.0004335088,0.0003436258,0.0000592066,0.00001612517,0.00004833307,0.00001853187,0.0001095325,0.9934949,0.00005734026,0.0001800224,0.004810778],"study_design_scores_gemma":[0.00007932931,0.002860736,0.008846163,0.000008480462,0.00004225695,0.000298418,0.00002216143,0.0007259534,0.9836746,0.00001524554,0.00342148,0.000005192909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995446,0.001968871,0.0007172957,0.00007022161,0.00003749405,0.00003254183,0.0002882539,0.0001458817,0.001293428],"genre_scores_gemma":[0.9918657,0.001893461,0.001470747,0.0001136518,0.0000194227,0.00005849133,0.001301914,0.00002786656,0.003248798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001219859,"threshold_uncertainty_score":0.003551841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02605109437159761,"score_gpt":0.3313813454030475,"score_spread":0.3053302510314499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}