{"id":"W2151918137","doi":"10.1158/0008-5472.can-06-0018","title":"IMC-EB10, an Anti-FLT3 Monoclonal Antibody, Prolongs Survival and Reduces Nonobese Diabetic/Severe Combined Immunodeficient Engraftment of Some Acute Lymphoblastic Leukemia Cell Lines and Primary Leukemic Samples","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Center for Research Resources; Wellcome Trust; Leukemia and Lymphoma Society","keywords":"Monoclonal antibody; Cancer research; Nod; Leukemia; Antibody; In vivo; Cell sorting; Cell culture; Acute lymphocytic leukemia; Immunotherapy; Medicine; Immunology; Biology; Immune system; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00164463,0.0005449312,0.001142877,0.0007337811,0.0004191874,0.0001679401,0.0005401117,0.0003318199,0.00009825345],"category_scores_gemma":[0.0001782371,0.0004622104,0.0001300846,0.0008139886,0.001851869,0.0004072728,0.0008219571,0.0008166301,0.00001483238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002887891,"about_ca_system_score_gemma":0.004980185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004650872,"about_ca_topic_score_gemma":0.0000411617,"domain_scores_codex":[0.9940628,0.0004364832,0.0008865198,0.001229199,0.001851988,0.001533028],"domain_scores_gemma":[0.9965648,0.0009029229,0.000217215,0.0008219408,0.0009396999,0.0005534081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002626511,0.0006799086,0.01781186,0.001263009,0.0002529562,0.0001641087,0.0004160973,0.0002021254,0.973146,0.0002951679,0.001034305,0.002107941],"study_design_scores_gemma":[0.0237217,0.004646122,0.3213242,0.001234766,0.0004940712,0.0003240182,0.0009599019,0.008662898,0.6358438,0.0007589409,0.0008854824,0.001144111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892819,0.007366221,0.00003358802,0.0006556165,0.0001892557,0.001690132,0.0003072039,0.00008186435,0.0003942115],"genre_scores_gemma":[0.9913403,0.005427459,0.0008178774,0.00005971438,0.0003969038,0.00026278,0.0003989119,0.0001227806,0.001173217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3373022,"threshold_uncertainty_score":0.999783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02605109437159761,"score_gpt":0.3313813454030475,"score_spread":0.3053302510314499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}