{"id":"W2151923418","doi":"10.1111/j.1365-2958.2006.05462.x","title":"MvfR, a key <i>Pseudomonas aeruginosa</i> pathogenicity LTTR‐class regulatory protein, has dual ligands","year":2006,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":306,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; Massachusetts General Hospital","keywords":"Virulence; Biology; Pseudomonas aeruginosa; Quorum sensing; Gene; Pyocyanin; Transcriptional regulation; Mutant; Regulator; Regulation of gene expression; Function (biology); Cell biology; Gene expression; Microbiology; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141188,0.0005022474,0.0002932411,0.0001484286,0.0001856712,0.000338992,0.0002438114,0.0004096288,0.001373148],"category_scores_gemma":[0.0001275738,0.000110163,0.0003108185,0.0001077811,0.0002745879,0.0002142251,0.0003001922,0.0004067423,0.000645045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004602032,"about_ca_system_score_gemma":0.0002085112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009354206,"about_ca_topic_score_gemma":0.0006173839,"domain_scores_codex":[0.9998258,0.00002004046,0.000008061779,0.0000436291,0.00005344132,0.00004913049],"domain_scores_gemma":[0.9998748,0.00001339831,0.0000462241,0.0000112617,0.00001539942,0.00003889543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001903489,0.000005404317,0.0001922503,0.00001174116,9.35404e-7,0.00004033834,0.000004783542,0.00001584523,0.9988779,0.00007505302,0.00002299073,0.0007336293],"study_design_scores_gemma":[0.00000831183,0.0002197953,0.007564598,0.000004164371,0.000007165792,0.001018951,0.0000289653,0.0007127509,0.9858846,0.0000643077,0.004479705,0.000006695522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743319,0.00280429,0.01861061,0.0004254182,0.0000512691,0.00004183505,0.0005378303,0.0005554135,0.002641507],"genre_scores_gemma":[0.9926283,0.0003956595,0.004028426,0.00009543599,0.00002584217,0.00001312389,0.0005935401,0.00003190152,0.00218766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001373148,"threshold_uncertainty_score":0.004593611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005073390450087944,"score_gpt":0.1834353938833413,"score_spread":0.1783620034332534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}