{"id":"W2151923418","doi":"10.1111/j.1365-2958.2006.05462.x","title":"MvfR, a key <i>Pseudomonas aeruginosa</i> pathogenicity LTTR‐class regulatory protein, has dual ligands","year":2006,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":306,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"National Institute of Allergy and Infectious Diseases; Massachusetts General Hospital","keywords":"Virulence; Biology; Pseudomonas aeruginosa; Quorum sensing; Gene; Pyocyanin; Transcriptional regulation; Mutant; Regulator; Regulation of gene expression; Function (biology); Cell biology; Gene expression; Microbiology; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002658533,0.0004690799,0.0004254522,0.00008599537,0.0002326607,0.0000764666,0.0002723178,0.0007145248,0.00002796985],"category_scores_gemma":[0.00004149359,0.000464308,0.0003165095,0.0001542686,0.0004244874,0.000006788177,0.0003115331,0.0002366725,0.00005137709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003769427,"about_ca_system_score_gemma":0.0001636675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000142762,"about_ca_topic_score_gemma":0.0001488101,"domain_scores_codex":[0.9975052,0.0001784998,0.0005080634,0.0009283072,0.00009200221,0.0007879662],"domain_scores_gemma":[0.99874,0.000008637193,0.0002113089,0.0007637569,0.000153129,0.0001232183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001529255,0.0001186437,0.0002185008,0.0000176819,0.00007531105,0.000112839,0.00001517226,0.00001515838,0.9930435,0.0005281791,0.005342184,0.0003598874],"study_design_scores_gemma":[0.0008880763,0.0002869996,0.0003602099,0.00001902769,0.0000353268,0.0004236702,0.000009961363,0.000004033884,0.8500836,0.00005818386,0.1473382,0.0004926556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958428,0.001395187,0.0004581729,0.000576702,0.0003823509,0.000467421,0.0001421983,0.00006715157,0.0006679876],"genre_scores_gemma":[0.9947544,0.00001578145,0.001592741,0.001115811,0.0005113147,0.00002822301,0.001255646,0.00007650037,0.0006496135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1429599,"threshold_uncertainty_score":0.9997809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005073390450087944,"score_gpt":0.1834353938833413,"score_spread":0.1783620034332534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}