{"id":"W2152010314","doi":"10.1002/chem.200601784","title":"Optimal Attachment Position and Linker Length Promote Native‐like Character of Cavitand‐Based Template‐Assembled Synthetic Proteins (TASPs)","year":2007,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; University of British Columbia","keywords":"Linker; Cavitand; Chemistry; Guanidine; Sequence (biology); Helix (gastropod); Template; Stereochemistry; Peptide; Crystallography; Combinatorial chemistry; Glycine; Peptide sequence; Amino acid; Biochemistry; Nanotechnology; Supramolecular chemistry; Biology; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000195779,0.0002673156,0.0002025222,0.00007496345,0.00006569465,0.0001938465,0.0001762527,0.0002292843,0.0002635274],"category_scores_gemma":[0.0002821868,0.0001392063,0.0001694342,0.00007189982,0.000138994,0.0002020595,0.0001335248,0.0002965842,0.0001506138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353258,"about_ca_system_score_gemma":0.0001164797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002041165,"about_ca_topic_score_gemma":0.0003741907,"domain_scores_codex":[0.9998797,0.00002074924,0.00001248885,0.00003248809,0.00003087278,0.00002367938],"domain_scores_gemma":[0.9998513,0.0000356145,0.00004910008,0.000009424904,0.00002343411,0.00003094669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002041112,0.000009102852,0.00007950973,0.00001440811,0.000001886792,0.00001955809,0.00001113925,0.0002358943,0.9991224,0.0000289842,0.000005807442,0.0004508986],"study_design_scores_gemma":[0.000004130231,0.0001318159,0.0005125296,0.000001796074,0.000004112643,0.00004385028,0.000005753843,0.001292583,0.9976441,0.000009523148,0.0003468326,0.000002906394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964679,0.0002594705,0.00279492,0.00002067741,0.000006465975,0.00001422525,0.00003024667,0.00003818647,0.0003678474],"genre_scores_gemma":[0.993957,0.000142823,0.005365328,0.00001611859,0.000005258954,0.00001473912,0.000070305,0.00002106091,0.0004072239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0002673156,"threshold_uncertainty_score":0.001707375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008838714556056263,"score_gpt":0.2388584885273951,"score_spread":0.2300197739713388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}