{"id":"W2152041993","doi":"10.1095/biolreprod.113.109066","title":"Stability of DNA Methylation Patterns in Mouse Spermatogonia Under Conditions of MTHFR Deficiency and Methionine Supplementation1","year":2013,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University; Royal Victoria Regional Health Centre; McGill University Health Centre; Montreal Children's Hospital","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Methylenetetrahydrofolate reductase; DNA methylation; Biology; Methylation; Methionine; Internal medicine; Genetics; Molecular biology; Endocrinology; Gene; Gene expression; Allele; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002100563,0.000280997,0.000317566,0.0007043268,0.0002159311,0.0002910913,0.0002398041,0.000398824,0.001239263],"category_scores_gemma":[0.000161723,0.0003018291,0.0003811482,0.0002910164,0.0002433238,0.0001877117,0.0001985042,0.0004805429,0.000409658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002226761,"about_ca_system_score_gemma":0.0001759025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001487581,"about_ca_topic_score_gemma":0.002049459,"domain_scores_codex":[0.9997993,0.00002087055,0.00002153297,0.00006957692,0.00005934724,0.00002936565],"domain_scores_gemma":[0.9997341,0.00002499413,0.00009205536,0.0000278637,0.00004878051,0.00007233023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001281761,0.000007710139,0.0009182915,0.00002541386,0.000008443601,0.00001945831,0.00002939575,0.00001186737,0.9979608,0.00001817742,0.00001314353,0.0008591533],"study_design_scores_gemma":[0.00002609939,0.0009530373,0.09479651,0.00001878557,0.0000861739,0.0005499654,0.0001360842,0.0003244909,0.9000897,0.00008713033,0.002912601,0.0000194333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857035,0.007233322,0.003205182,0.00008812091,0.00003791251,0.00004981087,0.002505629,0.0001707027,0.001005676],"genre_scores_gemma":[0.9826826,0.003710354,0.004471712,0.00009331307,0.00001973539,0.00009967648,0.003395451,0.00006988973,0.005457293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001487581,"threshold_uncertainty_score":0.004145741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068949492954545,"score_gpt":0.2937838916779478,"score_spread":0.2730943967484024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}