{"id":"W2152084367","doi":"10.1093/toxsci/kfg060","title":"Mechanisms of Ocular Toxicity Using the in Vitro Bovine Lens and Sodium Dodecyl Sulfate as a Chemical Model","year":2003,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; Western University","funders":"","keywords":"Sodium dodecyl sulfate; Lens (geology); Toxicity; Lens Fiber; Chemistry; In vitro; Pulmonary surfactant; Confocal microscopy; Confocal; Biophysics; Mitochondrion; Biochemistry; Biology; Cell biology; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003980692,0.0006870519,0.0003088665,0.000427124,0.0002909817,0.0004293875,0.0003124463,0.0004862209,0.0009266964],"category_scores_gemma":[0.0002500601,0.0001901018,0.0004230675,0.0002387317,0.0003544244,0.0004657549,0.0002459135,0.0005101833,0.0002214987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008475124,"about_ca_system_score_gemma":0.0003419864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005535509,"about_ca_topic_score_gemma":0.005913729,"domain_scores_codex":[0.9996469,0.00009509385,0.00004300829,0.00005727124,0.0001065111,0.00005113141],"domain_scores_gemma":[0.9997383,0.00005755529,0.00009123037,0.00002673287,0.00006223745,0.00002403828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008503789,0.0000298325,0.0004850711,0.0001519444,0.00001524195,0.00009991162,0.00004269698,0.00009732095,0.9976245,0.000113365,0.00003009551,0.001225079],"study_design_scores_gemma":[0.000007699445,0.0009363159,0.008498218,0.00002303853,0.00003693222,0.0002827275,0.0001137718,0.0006272856,0.9872591,0.00009632787,0.00211099,0.000007590233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9594269,0.02409379,0.0121471,0.0003555936,0.0001025006,0.000117989,0.0006576697,0.00009956936,0.002998812],"genre_scores_gemma":[0.9857138,0.008004889,0.002923393,0.00009903438,0.00001849514,0.00008018566,0.0006019645,0.00001122521,0.002547053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005535509,"threshold_uncertainty_score":0.01100659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03849386973083855,"score_gpt":0.2849114831496449,"score_spread":0.2464176134188063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}