{"id":"W2152158810","doi":"10.1111/j.1365-2958.2011.07769.x","title":"Stage‐specific requirement for Isa1 and Isa2 proteins in the mitochondrion of <i>Trypanosoma brucei</i> and heterologous rescue by human and <i>Blastocystis</i> orthologues","year":2011,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Grantová Agentura České Republiky; Canadian Institute for Advanced Research","keywords":"Biology; Aconitase; Fumarase; Trypanosoma brucei; Mitochondrion; Cell biology; Alternative oxidase; Organelle; Blastocystis; Heterologous; Biochemistry; Gene; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009941697,0.0003428583,0.0002147995,0.0001663407,0.0001678548,0.0002951768,0.0001884087,0.0002817607,0.001298116],"category_scores_gemma":[0.0001067766,0.0002039864,0.0002655111,0.0001359702,0.0002087746,0.0001506075,0.0002890106,0.0005176587,0.000734237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003370161,"about_ca_system_score_gemma":0.0002312719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001927049,"about_ca_topic_score_gemma":0.002596084,"domain_scores_codex":[0.999885,0.00001196918,0.00001877245,0.00003030487,0.0000295338,0.00002446794],"domain_scores_gemma":[0.9998513,0.00001988042,0.00004756379,0.00001909279,0.00001638257,0.00004579503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002949562,0.000004188171,0.0000651821,0.00001292008,0.000001146452,0.00002065353,0.00001043672,0.000005717785,0.9997101,0.00002106295,0.00001561782,0.0001034113],"study_design_scores_gemma":[0.00002134366,0.0001758998,0.02078751,0.00001082915,0.00002057658,0.0006549573,0.00008546703,0.0005438122,0.9738607,0.00003877852,0.003791098,0.000008990788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954335,0.001132529,0.001155815,0.0001177543,0.00002738212,0.0000154056,0.0009587845,0.00007539967,0.001083364],"genre_scores_gemma":[0.9885527,0.000609993,0.001636749,0.00009220071,0.00001071912,0.0000417742,0.003685237,0.0000931469,0.005277406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001927049,"threshold_uncertainty_score":0.004342675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02158698047101884,"score_gpt":0.227957846305051,"score_spread":0.2063708658340322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}