{"id":"W2152254495","doi":"10.1002/jgm.867","title":"A convenient plasmid system for construction of helper‐dependent adenoviral vectors and its application for analysis of the breast‐cancer‐specific mammaglobin promoter","year":2006,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; McMaster University","funders":"","keywords":"Mammaglobin; Enhancer; Plasmid; Vector (molecular biology); Transgene; Biology; Viral vector; Reporter gene; Expression cassette; Promoter; Computational biology; Molecular biology; Gene; Genetics; Transcription factor; Recombinant DNA; Gene expression; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008609375,0.00009342751,0.0002786368,0.0001066926,0.00005742178,0.000002619281,0.000208637,0.00005517203,0.000005732679],"category_scores_gemma":[0.00001588105,0.00005059756,0.0001098319,0.0001983216,0.0001652949,0.000003227754,0.00002390788,0.00005850385,5.943795e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004163598,"about_ca_system_score_gemma":0.0000784451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002376657,"about_ca_topic_score_gemma":0.0000509598,"domain_scores_codex":[0.9989622,0.00009817775,0.0004448733,0.0001101106,0.0002649348,0.0001196991],"domain_scores_gemma":[0.9987484,0.00003874334,0.0005416679,0.000194729,0.0004426552,0.00003378465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00307928,0.00003207013,0.0009786297,0.00007276328,0.0004148837,9.923205e-8,0.00006959226,0.0007052228,0.9924526,0.00003677607,0.0001268971,0.002031183],"study_design_scores_gemma":[0.001610704,0.001657287,0.003215587,0.00004508855,0.0006020947,0.0000749,0.000257503,0.0006502161,0.9915522,0.00002562625,0.0002588462,0.00004988831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892635,0.00408029,0.00490073,0.0008793239,0.0001229188,0.0006227642,0.0001235053,0.000001231327,0.000005778465],"genre_scores_gemma":[0.9991431,0.0003158136,0.00008185161,0.00001887244,0.0003541932,0.00002606383,0.00001631408,0.00001067142,0.00003311541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009879646,"threshold_uncertainty_score":0.2063309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01303258767368973,"score_gpt":0.2779039814055816,"score_spread":0.2648713937318919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}