{"id":"W2152355524","doi":"10.1080/10623320214734","title":"Regulation of the Glyoxalase Pathway in Human Brain Microvascular Endothelium: Effects of Troglitazone and Tertiary Butylhydroperoxide","year":2002,"lang":"en","type":"article","venue":"Endothelium","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Methylglyoxal; Troglitazone; Glutathione; Lactoylglutathione lyase; Glutathione reductase; Chemistry; Biochemistry; GPX4; Glutathione peroxidase; Enzyme; Peroxisome proliferator-activated receptor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662519,0.0002574894,0.0002561031,0.0001359518,0.0001416397,0.0002085842,0.0001255441,0.0002207071,0.0009860825],"category_scores_gemma":[0.0001662373,0.0001422969,0.0002993123,0.0001264935,0.0001720716,0.00021394,0.0001247229,0.000367129,0.000186585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002415225,"about_ca_system_score_gemma":0.000189522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001371079,"about_ca_topic_score_gemma":0.001830946,"domain_scores_codex":[0.9998934,0.00003494945,0.000009601533,0.0000199796,0.00001308243,0.00002883023],"domain_scores_gemma":[0.999909,0.00001886729,0.00002320404,0.00001411033,0.00001540316,0.00001938462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001077155,0.00008139996,0.000275029,0.00004957866,0.00001253755,0.0001205378,0.00003853659,0.00005450777,0.9968675,0.00003160588,0.00003616327,0.001355426],"study_design_scores_gemma":[0.00007752474,0.002459504,0.009811632,0.000006846276,0.00004214155,0.0002197304,0.00006692196,0.0004978165,0.9858315,0.00003378775,0.000946324,0.000006189857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996312,0.002358904,0.0006906455,0.00008011149,0.00003187363,0.00002178569,0.0001060535,0.00003141313,0.0003671933],"genre_scores_gemma":[0.996927,0.001191997,0.0009588769,0.00004306382,0.00001514509,0.00003752892,0.000178513,0.000005100851,0.0006428015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001371079,"threshold_uncertainty_score":0.003298759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006541969090617045,"score_gpt":0.2311430339327327,"score_spread":0.2246010648421156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}