{"id":"W2152368246","doi":"10.3899/jrheum.080813","title":"Safety and Efficacy of the Selective Costimulation Modulator Abatacept in Patients with Rheumatoid Arthritis Receiving Background Methotrexate: A 5-year Extended Phase IIB Study","year":2009,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Versus Arthritis; National Institute for Health and Care Research","keywords":"Abatacept; Medicine; Rheumatoid arthritis; Methotrexate; Placebo; Internal medicine; Adverse effect; Incidence (geometry); Arthritis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001299672,0.0001914983,0.0007774857,0.0002263155,0.0001659311,0.00001959889,0.0002044265,0.00007134179,0.00003798308],"category_scores_gemma":[0.0005746999,0.0001044815,0.00007609574,0.000425951,0.0002530149,0.0002160769,0.00004667952,0.000535245,0.000001404357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007386268,"about_ca_system_score_gemma":0.0001618005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009548086,"about_ca_topic_score_gemma":0.0001219657,"domain_scores_codex":[0.9973087,0.0008589294,0.000839712,0.0001650577,0.0005232751,0.000304334],"domain_scores_gemma":[0.9979246,0.0006347683,0.000611799,0.0003062458,0.0004067345,0.0001158439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02296774,0.002808897,0.9099515,0.00001791703,0.0004229789,0.00001192975,0.007220585,0.0001832842,0.0003250212,0.0002188306,0.00006771128,0.0558036],"study_design_scores_gemma":[0.04080871,0.005703447,0.9493932,0.0008438373,0.00001807669,0.0008138187,0.001624209,0.0002211953,0.0001397523,0.0002940021,0.00003182877,0.0001079801],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964792,0.0018131,0.0002243875,0.0004499114,0.00006741239,0.0009110823,0.000005572047,0.000008856954,0.00004047258],"genre_scores_gemma":[0.9926323,0.007030397,0.0002775488,0.00002699382,0.000004089187,0.000002108571,0.000002426385,0.00001818606,0.000005895317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05569562,"threshold_uncertainty_score":0.426063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159959342054759,"score_gpt":0.2917255082119914,"score_spread":0.2801259147914438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}