{"id":"W2152368246","doi":"10.3899/jrheum.080813","title":"Safety and Efficacy of the Selective Costimulation Modulator Abatacept in Patients with Rheumatoid Arthritis Receiving Background Methotrexate: A 5-year Extended Phase IIB Study","year":2009,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Versus Arthritis; National Institute for Health and Care Research","keywords":"Abatacept; Medicine; Rheumatoid arthritis; Methotrexate; Placebo; Internal medicine; Adverse effect; Incidence (geometry); Arthritis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002715057,0.0009578989,0.002308297,0.0002969582,0.0003983281,0.000649226,0.0005036994,0.001190076,0.001983056],"category_scores_gemma":[0.00111859,0.000347817,0.001514251,0.0003666815,0.0004458944,0.0005278728,0.0002312708,0.001582645,0.0005055816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004996877,"about_ca_system_score_gemma":0.0008168183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004560654,"about_ca_topic_score_gemma":0.0007704337,"domain_scores_codex":[0.9992902,0.0003530952,0.0000562306,0.00009012813,0.00008274228,0.0001275502],"domain_scores_gemma":[0.9990416,0.0001790859,0.0003080738,0.00008460209,0.00008583053,0.0003007453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.796698,0.03312936,0.01788018,0.001121169,0.002637014,0.0002588541,0.0002137371,0.0009770431,0.02750834,0.00007189415,0.0008804771,0.1186239],"study_design_scores_gemma":[0.3638348,0.5856002,0.0452349,0.00007488846,0.00131355,0.0002540843,0.00003512875,0.000674153,0.001614996,0.00004643447,0.001293958,0.0000229628],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936519,0.004463127,0.0002605234,0.0001276155,0.00004762653,0.0005628105,0.0002379658,0.00002934613,0.0006191093],"genre_scores_gemma":[0.9957087,0.001537283,0.0004930265,0.0004266312,0.0001756827,0.0006004504,0.0005869537,0.000004880549,0.0004663844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002715057,"threshold_uncertainty_score":0.01435876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159959342054759,"score_gpt":0.2917255082119914,"score_spread":0.2801259147914438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}