{"id":"W2152411469","doi":"","title":"Phase I study of docosahexaenoic acid-paclitaxel: a taxane-fatty acid conjugate with a unique pharmacology and toxicity profile.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTO Manufacturing (Canada)","funders":"","keywords":"Paclitaxel; Taxane; Toxicity; Docosahexaenoic acid; Pharmacology; Pharmacokinetics; Neutropenia; Medicine; Chemotherapy; Gastroenterology; Internal medicine; Chemistry; Fatty acid; Polyunsaturated fatty acid; Breast cancer; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001258403,0.0002626613,0.0005106761,0.0002187711,0.0002277214,0.00004207726,0.0001961603,0.0001151406,0.00008481358],"category_scores_gemma":[0.0002618985,0.0002100299,0.0000414241,0.0004562306,0.0003098337,0.0002124131,0.00005600782,0.0004936939,0.000005777611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001356029,"about_ca_system_score_gemma":0.000114729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001691822,"about_ca_topic_score_gemma":0.0002777296,"domain_scores_codex":[0.996738,0.0008954042,0.0004241953,0.0005119473,0.0003982391,0.001032274],"domain_scores_gemma":[0.9985909,0.0001347013,0.0002169632,0.0003249052,0.0001730827,0.0005593805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03514722,0.03676873,0.07909141,0.002337127,0.001038335,0.0006636002,0.01250158,0.00001637524,0.6712646,0.0006931319,0.008431916,0.1520459],"study_design_scores_gemma":[0.02071739,0.005887506,0.02283434,0.0000216279,0.0001083541,0.00006719398,0.001182193,0.0000428057,0.9474466,0.0001190559,0.001266827,0.0003061066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910945,0.000376834,0.0001610055,0.001276055,0.0002164978,0.00561928,0.00004907755,0.00009187417,0.001114836],"genre_scores_gemma":[0.9959704,0.0000383481,0.0006667575,0.0005030615,0.0000626493,0.00265997,0.000007880647,0.0000379042,0.00005305276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2761819,"threshold_uncertainty_score":0.8564771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03537333244899311,"score_gpt":0.3273433946367946,"score_spread":0.2919700621878015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}