{"id":"W2152411469","doi":"","title":"Phase I study of docosahexaenoic acid-paclitaxel: a taxane-fatty acid conjugate with a unique pharmacology and toxicity profile.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTO Manufacturing (Canada)","funders":"","keywords":"Paclitaxel; Taxane; Toxicity; Docosahexaenoic acid; Pharmacology; Pharmacokinetics; Neutropenia; Medicine; Chemotherapy; Gastroenterology; Internal medicine; Chemistry; Fatty acid; Polyunsaturated fatty acid; Breast cancer; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003608094,0.000785597,0.000941525,0.0002218439,0.0002334521,0.0005394848,0.0004999869,0.0006560505,0.002263331],"category_scores_gemma":[0.0003225032,0.0002953742,0.0003988015,0.0003243932,0.0005140596,0.0003468832,0.0001877305,0.001703344,0.0005166514],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007535937,"about_ca_system_score_gemma":0.001016398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00053424,"about_ca_topic_score_gemma":0.001289647,"domain_scores_codex":[0.9998742,0.00004105228,0.00000671738,0.00002855413,0.00002085208,0.00002861962],"domain_scores_gemma":[0.9997606,0.00002704928,0.00006655217,0.00002450154,0.00001476389,0.0001066096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1480861,0.06869446,0.0106766,0.0008233416,0.0008452839,0.0007759757,0.0003564904,0.004541881,0.6288082,0.0006205125,0.002778953,0.1329923],"study_design_scores_gemma":[0.1567419,0.6946141,0.02124551,0.00005578368,0.0007867027,0.00215737,0.00009353759,0.00265208,0.1121117,0.0002529707,0.009252599,0.00003568079],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996086,0.001128627,0.0007863979,0.0001391462,0.00003389121,0.0006378336,0.0002999131,0.00003826686,0.0008500572],"genre_scores_gemma":[0.9925091,0.001285131,0.002237434,0.0002439595,0.00004874574,0.000896855,0.001249141,0.0000228813,0.001506905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002263331,"threshold_uncertainty_score":0.007571638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03537333244899311,"score_gpt":0.3273433946367946,"score_spread":0.2919700621878015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}