{"id":"W2152456558","doi":"10.1183/09031936.02.01762002","title":"BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives","year":2002,"lang":"en","type":"article","venue":"European Respiratory Journal","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; Institut National de la Santé et de la Recherche Médicale","keywords":"Fenfluramine; BMPR2; Medicine; Dexfenfluramine; Pulmonary hypertension; Internal medicine; Bone morphogenetic protein receptor; Mutation; Endocrinology; Germline mutation; Population; Cardiology; Gastroenterology; Bone morphogenetic protein; Receptor; Gene; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001957557,0.0002710029,0.0002684155,0.0005579253,0.00032411,0.0002167322,0.0001469405,0.0004436205,0.00184147],"category_scores_gemma":[0.001579632,0.00015688,0.000240855,0.0002134005,0.0002636153,0.000191426,0.0001812191,0.0002405137,0.0001970187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001156838,"about_ca_system_score_gemma":0.0001104774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008916282,"about_ca_topic_score_gemma":0.0009502468,"domain_scores_codex":[0.9997823,0.00004378535,0.00001942522,0.00004361085,0.00006370535,0.00004714783],"domain_scores_gemma":[0.9994956,0.000185529,0.0001328227,0.00002809673,0.0000547717,0.0001031223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004807291,0.0001193435,0.9142952,0.0000370643,0.0000636666,0.02973128,0.000758763,0.00007551488,0.04613678,0.00008560753,0.0001146141,0.008101418],"study_design_scores_gemma":[0.00006821055,0.0009515172,0.860616,0.00001176696,0.0001084639,0.1276584,0.0004420634,0.0003942966,0.008921972,0.0000962725,0.0007199426,0.00001118564],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996616,0.00006622858,0.0000782803,0.00001534931,0.000002258278,0.00000273987,0.0000108313,0.000002128198,0.0001606753],"genre_scores_gemma":[0.9997447,0.00003531663,0.00006851912,0.000014992,0.000007872949,0.000001567476,0.00001756477,0.000001291826,0.0001082027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00184147,"threshold_uncertainty_score":0.006160259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06887625490844262,"score_gpt":0.2799754865052668,"score_spread":0.2110992315968241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}